Rome2Rio

How to get fromFlorida Keys to Pensacolaby plane, bus (Greyhound, Flixbus), car, taxi, shuttle, or bus

Find Transport to Pensacola

See all options

There are 9 ways to get from Florida Keys to Pensacola by plane, bus (Greyhound, Flixbus), car, taxi, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Pensacola International Airport

    best
    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    7h 59m
    $149–416

  2. Drive  797.4 mi

    cheapest
    1. Drive from Florida Keys to Pensacolacar car 797.4 mi
    14h 21m
    $146–211

  3. Bus

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Mobilebus bus
    4. Take the bus from Loxley to Pensacolabus bus
    27h 27m
    $237–372

  4. Fly Key West International Airport to Destin–Fort Walton Beach Airport, taxi

    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    2. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    8h 5m
    $282–664

  5. Shuttle to Miami International Airport, fly to Pensacola International Airport

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    8h 31m
    $194–426

  6. Shuttle to Miami International Airport, fly to Destin–Fort Walton Beach Airport, taxi

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    3. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    8h 31m
    $322–654

  7. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Pensacola International Airport

    1. Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Pensacola International Airport (PNS)plane plane FLL - PNS
    9h 13m
    $304–496

  8. Fly Key West International Airport to Mobile Regional Airport, bus

    1. Fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB)plane plane EYW - MOB
    2. Take the bus from Mobile to Pensacolabus bus
    9h 32m
    $252–669

  9. Bus via Biloxi

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Biloxi Transit Centerbus bus
    4. Take the bus from Biloxi to Pensacolabus bus
    32h 48m
    $249–409

Key West International Airport (EYW) to Pensacola International Airport (PNS) flights

Calendar61Weekly Planes
Duration5h 47mAverage Duration
Ticket$55Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Florida Keys to Pensacola.ExpandLaunch map view
  • Distance: 567.7 mi
  • Duration: 7h 59m

What companies run services between Florida Keys, FL, USA and Pensacola, FL, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to Pensacola International Airport (PNS) every 3 hours. Alternatively, you can take a vehicle from Florida Keys to Pensacola via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Loxley in around 27h 27m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There