There are 9 ways to get from Florida Keys to Pensacola by plane, bus (Greyhound, Flixbus), car, taxi, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Key West International Airport to Pensacola International Airport
best- Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane EYW - PNS
8h 6m$144–386Bus via Sandy Springs
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Mobilebus
- Take the bus from Loxley to Pensacolabus
27h 12m$235–362Drive 797.4 mi
- Drive from Florida Keys to Pensacolacar 797.4 mi
14h 21m$146–211Fly Key West International Airport to Destin–Fort Walton Beach Airport, taxi
- Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane EYW - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi
8h 42m$272–614Shuttle to Miami International Airport, fly to Pensacola International Airport
- Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airport
- Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane MIA - PNS
8h 30m$199–456Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Pensacola International Airport
- Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Pensacola International Airport (PNS)plane FLL - PNS
9h 8m$304–486Shuttle to Miami International Airport, fly to Destin–Fort Walton Beach Airport, taxi
- Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airport
- Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane MIA - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi
8h 26m$327–684Fly Key West International Airport to Mobile Regional Airport, bus
- Fly from Key West International Airport (EYW) to Mobile Regional Airport (MOB)plane EYW - MOB
- Take the bus from Mobile to Pensacolabus
9h 23m$242–619Bus
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Tallahasseebus
- Take the bus from Tallahassee to Mobile Bus Stationbus
- Take the bus from Mobile to Pensacolabus
29h 58m$182–299
Key West International Airport (EYW) to Pensacola International Airport (PNS) flights
Comparing Your Travel Options
The cheapest way to get from Florida Keys to Pensacola is to drive which costs $140 - $210 and takes 14h 21m.
The fastest way to get from Florida Keys to Pensacola is to fly which takes 8h 6m and costs $140 - $390.
No, there is no direct bus from Florida Keys to Pensacola. However, there are services departing from Sugarloaf Key - Lower - Opposite Sugarloaf Lodge and arriving at Pensacola via Big Pine Key, Miami Airport Station, Atlanta and Loxley. The journey, including transfers, takes approximately 27h 12m.
The distance between Florida Keys and Pensacola is 571 miles. The road distance is 802 miles.
The best way to get from Florida Keys to Pensacola without a car is to bus via Sandy Springs which takes 27h 12m and costs $230 - $370.
It takes approximately 8h 6m to get from Florida Keys to Pensacola, including transfers.
Florida Keys to Pensacola bus services, operated by Greyhound USA, depart from Big Pine Key station.
The best way to get from Florida Keys to Pensacola is to fly which takes 8h 6m and costs $140 - $390. Alternatively, you can bus via Sandy Springs, which costs $230 - $370 and takes 27h 12m.
Florida Keys to Pensacola bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Florida Keys to Pensacola is 802 miles. It takes approximately 14h 21m to drive from Florida Keys to Pensacola.
What companies run services between Florida Keys, FL, USA and Pensacola, FL, USA?
American Airlines and Delta fly from Key West International Airport (EYW) to Pensacola International Airport (PNS) every 3 hours. Alternatively, you can take a vehicle from Florida Keys to Pensacola via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Loxley in around 27h 12m.
- Website
- delta.com
Flights from Key West International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $60–310
Flights from Key West International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $75–400
Flights from Fort Lauderdale–Hollywood International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $65–350
Flights from Key West International Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $80–410
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- $100–170
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Miami Airport Station to Tallahassee
- Ave. Duration
- 13h 55m
- Frequency
- Once daily
- Estimated price
- $85–140
- Website
- Greyhound
Bus from Tallahassee to Mobile Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Website
- Greyhound
- Ave. Duration
- 1h 10m
- Estimated price
- $120–150
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 1584+ hotels available in Pensacola.


