What is the cheapest way to get from Florida Keys to Sanibel Island?

The cheapest way to get from Florida Keys to Sanibel Island is to drive which costs $45 - $70 and takes 5h 47m.

What is the fastest way to get from Florida Keys to Sanibel Island?

The fastest way to get from Florida Keys to Sanibel Island is to drive which takes 5h 47m and costs $45 - $70.

Is there a direct bus between Florida Keys and Sanibel Island?

No, there is no direct bus from Florida Keys to Sanibel Island. However, there are services departing from Sugarloaf Key - Lower - Opposite Sugarloaf Lodge and arriving at Cape Coral Transfer Center via Big Pine Key, Miami Airport Station and Rosa Parks Transportation Ctr. The journey, including transfers, takes approximately 11h 22m.

Is there a direct ferry between Florida Keys and Sanibel Island?

No, there is no direct ferry from Florida Keys to Sanibel Island. However, there are services departing from Key West, FL and arriving at Fort Myers Beach, FL via . The journey, including transfers, takes approximately 6h 7m.

How far is it from Florida Keys to Sanibel Island?

The distance between Florida Keys and Sanibel Island is 167 miles. The road distance is 264.8 miles.

How do I travel from Florida Keys to Sanibel Island without a car?

The best way to get from Florida Keys to Sanibel Island without a car is to ferry which takes 6h 7m and costs $160 - $180.

How long does it take to get from Florida Keys to Sanibel Island?

It takes approximately 6h 7m to get from Florida Keys to Sanibel Island, including transfers.

Where do I catch the Florida Keys to Sanibel Island bus from?

Florida Keys to Sanibel Island bus services, operated by Greyhound USA, depart from Big Pine Key station.

Where does the Florida Keys to Sanibel Island bus arrive?

Florida Keys to Sanibel Island bus services, operated by Greyhound USA, arrive at Miami Airport Station.

Can I drive from Florida Keys to Sanibel Island?

Yes, the driving distance between Florida Keys to Sanibel Island is 265 miles. It takes approximately 5h 47m to drive from Florida Keys to Sanibel Island.

Where can I stay near Sanibel Island?

There are 4321+ hotels available in Sanibel Island.

Florida Keys to Sanibel Island - 3 ways to travel via ferry, bus, and car

How to get fromFlorida Keys to Sanibel Island

Travel from

See all options

Search accommodation with Expedia

There are 3 ways to get from Florida Keys to Sanibel Island by ferry, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Ferry
best
1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry Key West
6h 7m
$162–179
Drive 263.3 mi
cheapest
1. Drive from Florida Keys to Sanibel Islandcar 263.3 mi
5h 47m
$48–70
Bus
1. Take the bus from Big Pine Key to Miami Airport Stationbus Greyhound US0720s
2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus FlixBus 2421
11h 22m
$93–147

Questions & Answers

Map of how to get from Florida Keys to Sanibel Island.

Launch map view

Distance: 166.2 mi
Duration: 6h 7m

What companies run services between Florida Keys, FL, USA and Sanibel Island, FL, USA?

Key West Express operates a ferry from Key West, FL to Fort Myers Beach, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a vehicle from Florida Keys to Sanibel Island via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 11h 22m.

Bus operators

Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.