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How to get fromFlorida Keys to Tampaby bus, plane, shuttle, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Florida Keys to Tampa by bus, plane, shuttle, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Key West International Airport, fly to Tampa, line 10 bus

    best
    1. Take the bus from Sugarloaf Key - Lower - Opposite Sugarloaf Lodge to Summerland Key - Mote Marine Labbus bus
    2. Fly from Key West International Airport (EYW) to Tampa (TPA)plane plane EYW - TPA
    3. Take the bus from TPA Internat'l Airport Post Office to Cass St @ Gasparilla Plazabus bus
    5h
    $164–506

  2. Bus

    cheapest
    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the bus from Miami Airport Station to Tampa Bus Stationbus bus FlixBus 2421 / ...
    12h 18m
    $67–134

  3. Shuttle, bus

    1. Take a shuttle bus from Summerland Key - Mote Marine Lab to Miami, FL - International Airportshuttle bus To the Airports
    2. Take the bus from Miami Airport to University of South Florida - 3801 USF Holly Drbus bus Miami
    12h 3m
    $226–328

  4. Bus, train

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Tampatrain train Floridian
    12h 8m
    $100–210

  5. Drive 375.3 mi

    1. Drive from Florida Keys to Tampacar car 375.3 mi
    7h 43m
    $69–99

  6. Fly Key West International Airport to Saint Petersburg–Clearwater International Airport, line 300 bus

    1. Fly from Key West International Airport (EYW) to Saint Petersburg–Clearwater International Airport (PIE)plane plane EYW - PIE
    2. Take the bus from Psta 34Th St Complex - Shelter - D to Jackson St + Franklin St Nbus bus
    6h 8m
    $138–380

  7. Shuttle to Miami International Airport, fly to Tampa

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Tampa (TPA)plane plane MIA - TPA
    7h 56m
    $904–1,286

Florida Keys to Tampa by foot, bus, and shuttle

Calendar7Weekly Services
Duration12h 3mAverage Duration
Ticket$226Cheapest Price
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Questions & Answers

Map of how to get from Florida Keys to Tampa.ExpandLaunch map view
  • Distance: 284.1 mi
  • Duration: 5h

What companies run services between Florida Keys, FL, USA and Tampa, FL, USA?

You can take a vehicle from Florida Keys to Tampa Bus Station via Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 12h 18m.

Airlines
Train operators
Bus operators

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