Rome2Rio

How to get fromFlorida Panhandle to Fort Myersby car, bus, or plane

Find Transport to Fort Myers

See all options

There are 8 ways to get from Florida Panhandle to Fort Myers by car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Florida Panhandle to Tallahasseecar car
    2. Take the bus from Tallahassee to Fort Myersbus bus Houston
    9h 12m
    $91–126

  2. Drive  416.4 mi

    cheapest
    1. Drive from Florida Panhandle to Fort Myerscar car 416.4 mi
    7h 53m
    $76–110

  3. Drive to Tallahassee, fly to Ft. Myers

    1. Drive from Florida Panhandle to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Ft. Myers (RSW)plane plane TLH - RSW
    7h 6m
    $108–520

  4. Drive, bus via Tampa

    1. Drive from Florida Panhandle to Capital Circle NW and Commonwealth Boulevardcar car
    2. Take the bus from Tallahassee to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    13h 10m
    $78–127

  5. Drive to Northwest Florida Beaches International Airport, fly to Ft. Myers

    1. Drive from Florida Panhandle to Northwest Florida Beaches International Airport (ECP)car car
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    7h 14m
    $108–570

  6. Drive to Tallahassee, fly to Miami International Airport, bus

    1. Drive from Florida Panhandle to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Miami International Airport (MIA)plane plane TLH - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    7h 10m
    $85–385

  7. Drive to Dothan Regional Airport, fly to Ft. Myers

    1. Drive from Florida Panhandle to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Ft. Myers (RSW)plane plane DHN - RSW
    8h 37m
    $108–516

  8. Drive to Tallahassee, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Drive from Florida Panhandle to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TLH - FLL
    3. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    6h 18m
    $251–900

Tallahassee (TLH) to Ft. Myers (RSW) flights

Calendar58Weekly Planes
Duration5h 19mAverage Duration
Ticket$95Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Florida Panhandle to Fort Myers.ExpandLaunch map view
  • Distance: 491.7 mi
  • Duration: 9h 12m

What companies run services between Florida Panhandle, FL, USA and Fort Myers, FL, USA?

There is no direct connection from Florida Panhandle to Fort Myers. However, you can drive to Tallahassee then take the bus to Fort Myers. Alternatively, you can drive from Florida Panhandle to Fort Myers in around 7h 53m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound