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How to get fromFlorida Panhandle to Port Saint Lucieby car, bus, plane, or taxi

Find Transport to Port Saint Lucie

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There are 8 ways to get from Florida Panhandle to Port Saint Lucie by car, bus, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Florida Panhandle to Tallahassee - FSU - Old St Augustine at Intramural Fieldcar car
    2. Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Kissimmee -1471 East Osceola Parkwaybus bus
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    9h 28m
    $105–185

  2. Drive, bus via Oak Ridge (Flixbus)

    cheapest
    1. Drive from Florida Panhandle to Capital Circle NW and Commonwealth Boulevardcar car
    2. Take the bus from Tallahassee to Orlandobus bus
    3. Take the bus from Orlando to Port St Luciebus bus
    12h 39m
    $71–127

  3. Drive 412.8 mi

    1. Drive from Florida Panhandle to Port Saint Luciecar car 412.8 mi
    7h 30m
    $76–109

  4. Drive to Tallahassee, fly to Miami International Airport, bus

    1. Drive from Florida Panhandle to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Miami International Airport (MIA)plane plane TLH - MIA
    3. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    6h 43m
    $103–421

  5. Drive to Northwest Florida Beaches International Airport, fly to Melbourne International Airport, taxi, bus

    1. Drive from Florida Panhandle to Northwest Florida Beaches International Airport (ECP)car car
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Melbourne International Airport (MLB)plane plane ECP - MLB
    3. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    4. Take the bus from Sebastian to Port St Luciebus bus
    9h 21m
    $171–518

  6. Drive to Tallahassee, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Drive from Florida Panhandle to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TLH - FLL
    3. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    6h 29m
    $250–910

  7. Drive to Destin–Fort Walton Beach Airport, fly to Miami International Airport, bus

    1. Drive from Florida Panhandle to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    3. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    7h 55m
    $112–413

  8. Drive to Northwest Florida Beaches International Airport, fly to President Donald J. Trump International Airport, bus

    1. Drive from Florida Panhandle to Northwest Florida Beaches International Airport (ECP)car car
    2. Fly from Northwest Florida Beaches International Airport (ECP) to President Donald J. Trump International Airport (PBI)plane plane ECP - PBI
    3. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    10h 19m
    $109–482

Tallahassee (TLH) to Miami International Airport (MIA) flights

Calendar28Weekly Planes
Duration1h 28mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

Map of how to get from Florida Panhandle to Port Saint Lucie.ExpandLaunch map view
  • Distance: 436.3 mi
  • Duration: 9h 28m

What companies run services between Florida Panhandle, FL, USA and Port Saint Lucie, FL, USA?

There is no direct connection from Florida Panhandle to Port Saint Lucie. However, you can drive to Tallahassee - FSU - Old St Augustine at Intramural Field, take the bus to Kissimmee -1471 East Osceola Parkway, then take the bus to Fort Pierce. Alternatively, you can drive from Florida Panhandle to Port Saint Lucie in around 7h 30m.

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