There are 7 ways to get from Florida to Cape Girardeau by plane, bus, taxi, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando Sanford to Cape Girardeau Municipal Airport
best- Fly from Orlando Sanford (SFB) to Cape Girardeau Municipal Airport (CGI)plane SFB - CGI
3h 7m$274–951Fly Jacksonville to Lambert–St. Louis International Airport, bus
cheapest- Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane JAX - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 57m$125–594Bus, taxi
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus
- Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi
17h 1m$223–336Drive 756.5 mi
- Drive from Jacksonville to Cape Girardeaucar 756.5 mi
13h 58m$139–200Fly Orlando to Lambert–St. Louis International Airport, bus
- Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane MCO - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
8h 1m$210–363Fly Tampa to Lambert–St. Louis International Airport, bus
- Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane TPA - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 58m$580–2,043Bus
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Cape Girardeaubus
21h 7m$152–252
Orlando Sanford (SFB) to Cape Girardeau Municipal Airport (CGI) flights
Comparing Your Travel Options
The cheapest way to get from Florida to Cape Girardeau is to drive which costs $130 - $200 and takes 13h 58m.
The fastest way to get from Florida to Cape Girardeau is to fly which takes 3h 7m and costs $270 - $950.
No, there is no direct bus from Florida to Cape Girardeau. However, there are services departing from Newnan St + Ashley St and arriving at Cape Girardeau via Jacksonville, Atlanta Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 21h 7m.
The distance between Florida and Cape Girardeau is 790 miles. The road distance is 760.9 miles.
The best way to get from Florida to Cape Girardeau without a car is to bus and taxi which takes 17h 1m and costs $220 - $340.
It takes approximately 3h 7m to get from Florida to Cape Girardeau, including transfers.
Florida to Cape Girardeau bus services, operated by Flixbus USA, depart from Jacksonville station.
The best way to get from Florida to Cape Girardeau is to fly which takes 3h 7m and costs $270 - $950. Alternatively, you can bus, which costs $150 - $260 and takes 21h 7m.
Florida to Cape Girardeau bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Cape Girardeau is 1h behind Florida. It is currently 4:32 PM in Florida and 3:32 PM in Cape Girardeau.
What companies run services between Florida, USA and Cape Girardeau, MO, USA?
Corporate Flight Management Inc flies from Orlando Sanford (SFB) to Cape Girardeau Municipal Airport (CGI) twice a week. Alternatively, you can take a bus from Newnan St + Ashley St to Cape Girardeau via JRTC Bay J, Jacksonville, Atlanta Bus Station, Memphis Bus Station, and Cape Girardeau in around 21h 7m.
- Website
- southwest.com
Flights from Jacksonville to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $95–550
Flights from Jacksonville to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 58m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Jacksonville to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- $120–600
Flights from Orlando to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $100–550
Flights from Orlando to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $100–550
Flights from Orlando to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 30m
- When
- Tuesday to Friday
- Estimated price
- $100–550
Flights from Orlando to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 4h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Tampa to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $100–550
Flights from Tampa to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 17m
- When
- Sunday
- Estimated price
- $100–600
Flights from Tampa to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 8h 21m
- Frequency
- 5 times a week
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Florida to Cape Girardeau is 761 miles. It takes approximately 13h 58m to drive from Florida to Cape Girardeau.
There are 25+ hotels available in Cape Girardeau.

