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How to get fromFlorida to La Crosseby plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

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There are 8 ways to get from Florida to La Crosse by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to La Crosse

    best
    1. Fly from Jacksonville (JAX) to La Crosse (LSE)plane plane JAX - LSE
    7h 18m
    $116–496

  2. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    32h 13m
    $220–456

  3. Train (Amtrak)

    1. Take the train from Jacksonville to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    42h 35m
    $487–1,123

  4. Drive  1,265.3 mi

    1. Drive from Jacksonville to La Crossecar car 1,265.3 mi
    22h 54m
    $231–334

  5. Fly Orlando to La Crosse

    1. Fly from Orlando (MCO) to La Crosse (LSE)plane plane MCO - LSE
    7h 28m
    $141–415

  6. Fly Tampa to La Crosse

    1. Fly from Tampa (TPA) to La Crosse (LSE)plane plane TPA - LSE
    7h 33m
    $131–525

  7. Fly Jacksonville to Minneapolis–Saint Paul International Airport, train

    1. Fly from Jacksonville (JAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane JAX - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 16m
    $164–686

  8. Fly Tampa to Minneapolis–Saint Paul International Airport, train

    1. Fly from Tampa (TPA) to Minneapolis–Saint Paul International Airport (MSP)plane plane TPA - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 18m
    $524–1,185

Florida to La Crosse by bus

Calendar7Weekly Buses
Duration32h 13mAverage Duration
Ticket$220Cheapest Price
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Questions & Answers

Map of how to get from Florida to La Crosse.ExpandLaunch map view
  • Distance: 1,086.5 mi
  • Duration: 7h 18m

What companies run services between Florida, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Jacksonville (JAX) to La Crosse (LSE) 4 times a day. Alternatively, you can take a bus from Newnan St + Ashley St to La Crosse via JRTC Bay J, Jacksonville, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 32h 13m.

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