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How to get fromFlorida to Mayo Clinicby plane, bus, bus (Flixbus, Greyhound), train, or car

Find Transport to Mayo Clinic

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There are 11 ways to get from Florida to Mayo Clinic by plane, bus, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to Minneapolis–Saint Paul International Airport, bus

    best
    1. Fly from Jacksonville (JAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane JAX - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 14m
    $162–653

  2. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    34h 21m
    $240–416

  3. Train, bus via Madison

    1. Take the train from Jacksonville to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    46h 22m
    $497–1,233

  4. Drive  1,309.4 mi

    1. Drive from Jacksonville to Mayo Cliniccar car 1,309.4 mi
    23h 23m
    $239–346

  5. Fly Tampa to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Tampa (TPA) to Minneapolis–Saint Paul International Airport (MSP)plane plane TPA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 13m
    $542–1,152

  6. Fly Orlando to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 18m
    $252–1,152

  7. Fly Miami International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Miami International Airport (MIA) to Minneapolis–Saint Paul International Airport (MSP)plane plane MIA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 20m
    $203–653

  8. Fly Fort Lauderdale–Hollywood International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Minneapolis–Saint Paul International Airport (MSP)plane plane FLL - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 25m
    $522–1,153

  9. Fly Ft. Myers to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Ft. Myers (RSW) to Minneapolis–Saint Paul International Airport (MSP)plane plane RSW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 35m
    $214–855

  10. Fly Orlando to General Mitchell International Airport, bus

    1. Fly from Orlando (MCO) to General Mitchell International Airport (MKE)plane plane MCO - MKE
    2. Take the bus from Milwaukee to Rochesterbus bus
    11h 49m
    $484–1,216

  11. Train, bus

    1. Take the train from Jacksonville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    47h 40m
    $560–1,433

Florida to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration34h 21mAverage Duration
Ticket$240Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florida to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,272.2 mi
  • Duration: 8h 14m

What companies run services between Florida, USA and Mayo Clinic, MN, USA?

You can take a bus from Newnan St + Ashley St to Mayo Clinic via JRTC Bay J, Jacksonville, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 34h 21m.

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