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How to get fromFlorida to Mayo Clinicby plane, bus, bus (Flixbus, Greyhound), train, or car

Find Transport to Mayo Clinic

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There are 10 ways to get from Florida to Mayo Clinic by plane, bus, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Jacksonville, bus

    best
    1. Fly from Jacksonville (JAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane JAX - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 50m
    $204–755

  2. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    34h 21m
    $256–471

  3. Train, bus via Madison

    1. Take the train from Jacksonville to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    46h 42m
    $577–1,233

  4. Drive 1,309.4 mi

    1. Drive from Jacksonville to Mayo Cliniccar car 1,309.4 mi
    23h 24m
    $239–346

  5. Fly from Orlando, bus

    1. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 58m
    $254–1,154

  6. Fly from Tampa, bus

    1. Fly from Tampa (TPA) to Minneapolis–Saint Paul International Airport (MSP)plane plane TPA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 59m
    $204–754

  7. Fly from Miami International Airport, bus

    1. Fly from Miami International Airport (MIA) to Minneapolis–Saint Paul International Airport (MSP)plane plane MIA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 5m
    $375–955

  8. Fly from Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Minneapolis–Saint Paul International Airport (MSP)plane plane FLL - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 12m
    $524–1,155

  9. Fly from Ft. Myers, bus

    1. Fly from Ft. Myers (RSW) to Minneapolis–Saint Paul International Airport (MSP)plane plane RSW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 19m
    $236–857

  10. Train, bus

    1. Take the train from Jacksonville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochester, MNbus bus
    47h 45m
    $660–1,413

Florida to Mayo Clinic by bus, train, and foot

Calendar7Weekly Services
Duration47h 45mAverage Duration
Ticket$660Cheapest Price
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Questions & Answers

Map of how to get from Florida to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,270 mi
  • Duration: 7h 50m

What companies run services between Florida, USA and Mayo Clinic, MN, USA?

You can take a bus from Newnan St + Ashley St to Mayo Clinic via JRTC Bay J, Jacksonville, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 34h 21m.

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Bus operators

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