There are 4 ways to get from Florida to Sanibel by bus (Flixbus), train, bus, car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Jacksonville to Orlando Bus Stationbus FlixBus N2434 / ...
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
8h 33m$107–158Drive 310.4 mi
cheapest- Drive from Jacksonville to Sanibelcar 310.4 mi
5h 59m$54–77Train, bus
- Take the train from Jacksonville to Tampatrain Floridian
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
11h 3m$210–316Bus via Wildwood
- Take the bus from Jacksonville to Wildwood Amtrak Stationbus Amtrak Thruway Connecting Service
- Take the bus from Wildwood to Fort Myersbus Houston
11h 21m
Comparing Your Travel Options
The cheapest way to get from Florida to Sanibel is to drive which costs $50 - $80 and takes 5h 59m.
The fastest way to get from Florida to Sanibel is to drive which takes 5h 59m and costs $50 - $80.
No, there is no direct bus from Florida to Sanibel. However, there are services departing from Jacksonville and arriving at Fort Myers Bus Stop via Orlando Bus Station. The journey, including transfers, takes approximately 8h 33m.
The distance between Florida and Sanibel is 378 miles. The road distance is 312.3 miles.
The best way to get from Florida to Sanibel without a car is to bus which takes 8h 33m and costs $100 - $160.
It takes approximately 8h 33m to get from Florida to Sanibel, including transfers.
Florida to Sanibel bus services, operated by Flixbus USA, depart from Jacksonville station.
Florida to Sanibel bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Florida to Sanibel is 312 miles. It takes approximately 5h 59m to drive from Florida to Sanibel.
There are 3729+ hotels available in Sanibel.
What companies run services between Florida, USA and Sanibel, FL, USA?
You can take a bus from Jacksonville to Sanibel via Orlando Bus Station and Fort Myers Bus Stop in around 8h 33m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Tampa
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $130–210
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 4h 35m
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $19–29
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Jacksonville to Wildwood Amtrak Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Website
- Amtrak
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Wildwood to Fort Myers
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- Omnibus Express
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