There are 5 ways to get from Florida to Sanibel by bus (Flixbus), train, bus, car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Tampa (Flixbus)
best- Take the bus from Jacksonville to Gainesvillebus
- Take the bus from Gainesville to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
9h 22m$101–151Drive 310.4 mi
cheapest- Drive from Jacksonville to Sanibelcar 310.4 mi
5h 59m$57–82Train, bus
- Take the train from Jacksonville to Tampatrain Floridian
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus FlixBus 2421
11h 48m$144–262Bus
- Take the bus from Jacksonville to Wildwood Amtrak Stationbus Amtrak Thruway Connecting Service
- Take the bus from Wildwood to Fort Myersbus Houston
11h 21m$162–218Bus via Orlando (Flixbus)
- Take the bus from Jacksonville to Orlando Bus Stationbus FlixBus 2433 / ...
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
11h 54m$98–151
Questions & Answers
The cheapest way to get from Florida to Sanibel is to drive which costs $55 - $85 and takes 5h 59m.
The fastest way to get from Florida to Sanibel is to drive which takes 5h 59m and costs $55 - $85.
No, there is no direct bus from Florida to Sanibel. However, there are services departing from Jacksonville and arriving at Fort Myers Bus Stop via Gainesville and Tampa Bus Station. The journey, including transfers, takes approximately 9h 22m.
The distance between Florida and Sanibel is 353 miles. The road distance is 312.3 miles.
The best way to get from Florida to Sanibel without a car is to bus via Tampa which takes 9h 22m and costs $100 - $160.
It takes approximately 9h 22m to get from Florida to Sanibel, including transfers.
Florida to Sanibel bus services, operated by Flixbus USA, depart from Jacksonville station.
Florida to Sanibel bus services, operated by Flixbus USA, arrive at Gainesville station.
Yes, the driving distance between Florida to Sanibel is 312 miles. It takes approximately 5h 59m to drive from Florida to Sanibel.
There are 3704+ hotels available in Sanibel.
What companies run services between Florida, USA and Sanibel, FL, USA?
You can take a bus from Jacksonville to Sanibel via Gainesville, Tampa Bus Station, and Fort Myers Bus Stop in around 9h 22m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Tampa
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Bus from Gainesville to Tampa Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $18–30
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Schedules at
- Flixbus USA
Bus from Jacksonville to Orlando Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Jacksonville to Wildwood Amtrak Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Amtrak
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Wildwood to Fort Myers
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- Omnibus Express
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide






