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How to get fromFlorida to Santeeby bus (Flixbus, Greyhound), train, car, plane, bus, or taxi

Find Transport to Santee

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There are 9 ways to get from Florida to Santee by bus (Flixbus, Greyhound), train, car, plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Jacksonville to Savannah Bus Stationbus bus FlixBus 2434 / ...
    2. Take the bus from Savannah to Orangeburgbus bus Ses 985 / ...
    5h 32m

  2. Drive 240.4 mi

    cheapest
    1. Drive from Jacksonville to Santeecar car 240.4 mi
    3h 56m
    $44–64

  3. Train, drive (Amtrak)

    1. Take the train from Jacksonville to Charleston Amtrak Stationtrain train Silver Meteor
    2. Drive from Charleston Amtrak Station to Santeecar car
    6h 39m
    $92–189

  4. Fly from Fort Lauderdale–Hollywood International Airport, drive

    1. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    4h 13m
    $182–1,119

  5. Bus, taxi (Greyhound)

    1. Take the bus from Jacksonville to Walterboro, SCbus bus Greyhound US0644S
    2. Take the taxi from Walterboro, SC to Santeetaxi taxi
    5h 33m
    $132–188

  6. Fly from Tampa, drive

    1. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    4h 24m
    $152–338

  7. Fly from Miami International Airport, drive

    1. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    4h 13m
    $513–1,019

  8. Fly from Orlando, drive

    1. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    4h 10m
    $77–278

  9. Fly from Ft. Myers, drive

    1. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    5h 30m
    $114–571

Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS) flights

Calendar27Weekly Planes
Duration3h 5mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Florida to Santee.ExpandLaunch map view
  • Distance: 264.7 mi
  • Duration: 5h 32m

What companies run services between Florida, USA and Santee, SC, USA?

You can take a bus from Jacksonville to Santee via Savannah Bus Station, Savannah, and Orangeburg in around 5h 32m.

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