There are 10 ways to get from Florida to Seneca by plane, taxi, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Tampa to Greenville–Spartanburg International Airport, taxi
best- Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane TPA - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
4h 30m$197–382Drive 343.8 mi
cheapest- Drive from Jacksonville to Senecacar 343.8 mi
7h 39m$63–91Bus, train
- Take the bus from Jacksonville to Charlotte Bus Stationbus FlixBus 2433
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain Crescent
12h 2m$162–257Fly Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport, taxi
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Greenville–Spartanburg International Airport (GSP)plane FLL - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
4h 27m$262–613Fly Orlando Sanford to Asheville Regional Airport, drive
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Senecacar
3h 57m$128–452Fly Miami International Airport to Greenville–Spartanburg International Airport, taxi
- Fly from Miami International Airport (MIA) to Greenville–Spartanburg International Airport (GSP)plane MIA - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
4h 30m$228–723Fly Fort Lauderdale–Hollywood International Airport to Asheville Regional Airport, drive
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane FLL - AVL
- Drive from Asheville-Airport-AVL to Senecacar
5h 22m$89–452Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, drive
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane PIE - AVL
- Drive from Asheville-Airport-AVL to Senecacar
5h 46m$77–394Bus, taxi
- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
12h 33m$185–289Bus, train via Camden
- Take the bus from Jacksonville to Camdenbus
- Take the bus from Camden to Charlotte Bus Stationbus
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain
16h 54m$180–270
Tampa (TPA) to Greenville–Spartanburg International Airport (GSP) flights
Comparing Your Travel Options
The cheapest way to get from Florida to Seneca is to drive which costs $60 - $95 and takes 7h 39m.
The fastest way to get from Florida to Seneca is to fly and drive which takes 3h 57m and costs $120 - $460.
The distance between Florida and Seneca is 540 miles. The road distance is 345.8 miles.
The best way to get from Florida to Seneca without a car is to bus and train which takes 12h 2m and costs $160 - $260.
It takes approximately 4h 30m to get from Florida to Seneca, including transfers.
Yes, the driving distance between Florida to Seneca is 346 miles. It takes approximately 7h 39m to drive from Florida to Seneca.
There are 177+ hotels available in Seneca.
What companies run services between Florida, USA and Seneca, SC, USA?
There is no direct connection from Florida to Seneca. However, you can take the line 30 bus to Airport Rental Car Center, walk to SkyConnect Rental Car Center Station, take the vehicle to SkyConnect Passenger Terminal Station, walk to Tampa (TPA) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take a bus from Jacksonville to Seneca via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & 23rd St, Charlotte Amtrak Station, and Clemson Amtrak Station in around 12h 2m.
- Website
- allegiantair.com
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 51m
- When
- Friday, Monday, Thursday, and Sunday
- Estimated price
- $120–700
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $55–360
Flights from Fort Lauderdale–Hollywood International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $75–430
Flights from Saint Petersburg–Clearwater International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–370
- Website
- aa.com
Flights from Tampa to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–600
Flights from Tampa to Greenville–Spartanburg International Airport via Miami International Airport
- Ave. Duration
- 4h 1m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $130–750
Flights from Miami International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $95–550
Flights from Miami International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $100–600
Flights from Fort Lauderdale–Hollywood International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–440
- Website
- delta.com
Flights from Tampa to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–600
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $130–750
Flights from Miami International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–600
Flights from Fort Lauderdale–Hollywood International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $80–450
- Website
- flybreeze.com
Flights from Tampa to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $65–210
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 5m
- When
- Monday and Friday
- Estimated price
- $130–310
- Website
- southwest.com
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $160–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Charlotte Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $60–90
- Schedules at
- Flixbus USA
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $60–90
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Jacksonville to Charlotte Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- Once daily
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- Twice daily
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Jacksonville to Camden
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $60–90
- Website
- Greyhound
Bus from Camden to Charlotte Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $14–21
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
- Ave. Duration
- 1h 2m
- Estimated price
- $100–170
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide










