There are 5 ways to get from Fort Mill to Santee by plane, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Columbia, drive
best- Fly from Charlotte Douglas International Airport (CLT) to Columbia (CAE)plane CLT - CAE
- Drive from Columbia-Airport-CAE to Santeecar
2h 26m$105–386Drive 136.1 mi
cheapest- Drive from Fort Mill to Santeecar 136.1 mi
2h 22m$25–35Bus
- Take the bus from Charlotte Bus Station to Orangeburgbus FlixBus 2433
4h 56m$150–199Fly to Charleston International Airport, drive
- Fly from Charlotte Douglas International Airport (CLT) to Charleston International Airport (CHS)plane CLT - CHS
- Drive from Charleston-Airport-CHS to Santeecar
2h 35m$120–447Bus via Park Rd & Carolina Place Pkwy
- Take the bus from Charlotte Bus Station to Orangeburgbus FlixBus 2433
5h 9m$138–186
Charlotte Douglas International Airport (CLT) to Columbia (CAE) flights
Comparing Your Travel Options
The cheapest way to get from Fort Mill to Santee is to drive which costs $24 - $35 and takes 2h 22m.
The fastest way to get from Fort Mill to Santee is to drive which takes 2h 22m and costs $24 - $35.
No, there is no direct bus from Fort Mill to Santee. However, there are services departing from Transit Center- Bay E and arriving at Orangeburg via Charlotte Bus Station. The journey, including transfers, takes approximately 4h 56m.
The distance between Fort Mill and Santee is 168 miles. The road distance is 136.9 miles.
The best way to get from Fort Mill to Santee without a car is to bus which takes 4h 56m and costs $150 - $200.
It takes approximately 2h 26m to get from Fort Mill to Santee, including transfers.
Fort Mill to Santee bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Fort Mill to Santee bus services, operated by Flixbus USA, arrive at Orangeburg station.
Yes, the driving distance between Fort Mill to Santee is 137 miles. It takes approximately 2h 22m to drive from Fort Mill to Santee.
There are 40+ hotels available in Santee.
What companies run services between Fort Mill, SC, USA and Santee, SC, USA?
Flixbus USA operates a bus from Charlotte Bus Station to Orangeburg once daily. Tickets cost $22–35 and the journey takes 2h 35m. Greyhound USA also services this route once daily.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Columbia
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- $35–300
Flights from Charlotte Douglas International Airport to Charleston International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $50–360
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $25–40
- Website
- Greyhound
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