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How to get fromFort Myers to Apalachicolaby bus, car, or plane

Find Transport to Apalachicola

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There are 7 ways to get from Fort Myers to Apalachicola by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive via Gainesville

    best
    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville to Tallahasseebus bus
    4. Drive from Ross Rd & Shelfer Rd to Apalachicolacar car
    11h 58m
    $105–183

  2. Bus, drive

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Drive from Ross Rd & Shelfer Rd to Apalachicolacar car
    12h 29m
    $72–128

  3. Drive 414.8 mi

    1. Drive from Fort Myers to Apalachicolacar car 414.8 mi
    7h 56m
    $76–110

  4. Bus to Miami International Airport, fly to Tallahassee, drive

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Tallahassee (TLH)plane plane MIA - TLH
    3. Drive from Tallahassee (TLH) to Apalachicolacar car
    7h 24m
    $103–452

  5. Fly Ft. Myers to Tallahassee, drive

    1. Fly from Ft. Myers (RSW) to Tallahassee (TLH)plane plane RSW - TLH
    2. Drive from Tallahassee (TLH) to Apalachicolacar car
    8h 38m
    $126–625

  6. Fly Ft. Myers to Northwest Florida Beaches International Airport, drive

    1. Fly from Ft. Myers (RSW) to Northwest Florida Beaches International Airport (ECP)plane plane RSW - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Apalachicolacar car
    8h 43m
    $108–507

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Tallahassee, drive

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Tallahassee (TLH)plane plane FLL - TLH
    3. Drive from Tallahassee (TLH) to Apalachicolacar car
    6h 31m
    $244–905

Miami International Airport (MIA) to Tallahassee (TLH) flights

Calendar28Weekly Planes
Duration1h 33mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Apalachicola.ExpandLaunch map view
  • Distance: 487.7 mi
  • Duration: 11h 58m

What companies run services between Fort Myers, FL, USA and Apalachicola, FL, USA?

There is no direct connection from Fort Myers to Apalachicola. However, you can take the taxi to Fort Myers 7-11, take the bus to University of South Florida - 3801 USF Holly Dr, take the bus to Gainesville, take the bus to Tallahassee, take the bus to Ross Rd & Shelfer Rd, then drive to Apalachicola. Alternatively, you can drive from Fort Myers to Apalachicola in around 7h 56m.

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