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How to get fromFort Myers to Big Pine Keyby ferry, bus, bus (Flixbus, Greyhound), car, or plane

Find Transport to Big Pine Key

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There are 5 ways to get from Fort Myers to Big Pine Key by ferry, bus, bus (Flixbus, Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry, bus

    best
    1. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    2. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    6h 44m
    $184–197

  2. Drive 244.7 mi

    cheapest
    1. Drive from Fort Myers to Big Pine Keycar car 244.7 mi
    5h 6m
    $45–65

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    7h 45m
    $46–82

  4. Bus, bus to Miami International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Take the bus from Fort Lauderdale Airport to Miami Airportbus bus
    3. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    4. Take the bus from Key West Airport to Big Pine Keybus bus
    6h 53m
    $59–257

  5. Bus to Tampa, fly, bus

    1. Take the bus from Fort Myers to Tampa Airportbus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    3. Take the bus from Key West Airport to Big Pine Keybus bus
    6h 38m
    $122–485

Fort Myers to Big Pine Key by bus

Calendar31Weekly Buses
Duration7h 45mAverage Duration
Ticket$46Cheapest Price
See schedules

Questions & Answers

Map of how to get from Fort Myers to Big Pine Key.ExpandLaunch map view
  • Distance: 184.3 mi
  • Duration: 6h 44m

What companies run services between Fort Myers, FL, USA and Big Pine Key, FL, USA?

You can take a bus from Fort Myers Bus Stop to Big Pine Key via Miami Airport Station in around 7h 45m.

Airlines
Bus operators
Ferry operators

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