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How to get fromFort Myers to Biloxiby plane, bus (Flixbus, Greyhound), car, bus, or train

Find Transport to Biloxi

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There are 7 ways to get from Fort Myers to Biloxi by plane, bus (Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT)plane plane RSW - GPT
    8h 8m
    $148–650

  2. Bus

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    18h 30m
    $103–174

  3. Drive  663.5 mi

    1. Drive from Fort Myers to Biloxicar car 663.5 mi
    11h 48m
    $122–175

  4. Bus to Tampa, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Gulfport-Biloxi Regional Airport (GPT)plane plane TPA - GPT
    7h 36m
    $142–548

  5. Bus to Sarasota–Bradenton International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Gulfport-Biloxi Regional Airport (GPT)plane plane SRQ - GPT
    8h 25m
    $187–864

  6. Fly Ft. Myers to Mobile Regional Airport, bus

    1. Fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB)plane plane RSW - MOB
    2. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    9h 18m
    $126–539

  7. Fly Ft. Myers to Louis Armstrong New Orleans International Airport, train

    1. Fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY)plane plane RSW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    8h 47m
    $286–1,180

Fort Myers to Biloxi by bus

Calendar14Weekly Buses
Duration18h 30mAverage Duration
Ticket$103Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Biloxi.ExpandLaunch map view
  • Distance: 547.8 mi
  • Duration: 8h 8m

What companies run services between Fort Myers, FL, USA and Biloxi, MS, USA?

Delta, United Airlines, and two other airlines fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Biloxi Transit Center via Tampa Bus Station, Tallahassee, and Mobile Bus Station in around 18h 30m.

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