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How to get fromFort Myers to Biloxiby bus, plane, bus (Greyhound, Flixbus), car, train, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Fort Myers to Biloxi by bus, plane, bus (Greyhound, Flixbus), car, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly to Gulfport-Biloxi Regional Airport

    best
    1. Take the bus from Fort Myers to Tampa Airportbus bus
    2. Fly from Tampa (TPA) to Gulfport-Biloxi Regional Airport (GPT)plane plane TPA - GPT
    5h 46m
    $243–1,031

  2. Bus via Tampa

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    18h 10m
    $103–205

  3. Bus

    1. Take the bus from Fort Myers to Tallahassee FSUbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    17h 48m
    $168–310

  4. Drive 663.5 mi

    1. Drive from Fort Myers to Biloxicar car 663.5 mi
    11h 48m
    $122–175

  5. Fly Ft. Myers to Gulfport-Biloxi Regional Airport

    1. Fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT)plane plane RSW - GPT
    8h 1m
    $158–650

  6. Bus to Sarasota–Bradenton International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Gulfport-Biloxi Regional Airport (GPT)plane plane SRQ - GPT
    8h 25m
    $168–667

  7. Fly Ft. Myers to Louis Armstrong New Orleans International Airport, train

    1. Fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY)plane plane RSW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    8h 47m
    $278–810

  8. Bus via Oak Ridge

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the bus from Orlando to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    21h 35m
    $125–227

Fort Myers to Biloxi by bus

Calendar28Weekly Buses
Duration18h 10mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Biloxi.ExpandLaunch map view
  • Distance: 579.6 mi
  • Duration: 5h 46m

What companies run services between Fort Myers, FL, USA and Biloxi, MS, USA?

You can take a vehicle from Fort Myers to Biloxi Transit Center via Fort Myers, Old St Augustine at Intramural Field, Tallahassee, and Mobile Bus Station in around 17h 48m. Alternatively, Delta, American Airlines, and Sun Country Airlines fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours.

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