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How to get fromFort Myers to Buffaloby plane, bus (Flixbus), bus, train, car, or taxi

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There are 10 ways to get from Fort Myers to Buffalo by plane, bus (Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Buffalo Niagara International Airport

    best
    1. Fly from Ft. Myers (RSW) to Buffalo Niagara International Airport (BUF)plane plane RSW - BUF
    7h 1m
    $178–883

  2. Fly Ft. Myers to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Ft. Myers (RSW) to Toronto Pearson International Airport (YYZ)plane plane RSW - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    11h 11m
    $120–509

  3. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York Midtown to Buffalobus bus
    38h 35m
    $286–433

  4. Bus, train via New York

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus
    2. Take the train from Fort Lauderdale Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    41h 13m
    $1,014–1,618

  5. Drive  1,324.3 mi

    1. Drive from Fort Myers to Buffalocar car 1,324.3 mi
    22h 53m
    $242–350

  6. Taxi to Punta Gorda Airport, fly to Niagara Falls International Airport

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Niagara Falls International Airport (IAG)plane plane PGD - IAG
    6h 3m
    $172–571

  7. Bus to Tampa, fly to Buffalo Niagara International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Buffalo Niagara International Airport (BUF)plane plane TPA - BUF
    9h 20m
    $219–713

  8. Fly Ft. Myers to Rochester, bus

    1. Fly from Ft. Myers (RSW) to Rochester (ROC)plane plane RSW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 35m
    $262–1,147

  9. Bus to Orlando, fly to Buffalo Niagara International Airport

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Fly from Orlando (MCO) to Buffalo Niagara International Airport (BUF)plane plane MCO - BUF
    11h 15m
    $223–454

  10. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    44h 19m
    $771–1,426

Fort Myers to Buffalo by bus (Flixbus)

Calendar5Weekly Buses
Duration38h 35mAverage Duration
Ticket$286Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Buffalo.ExpandLaunch map view
  • Distance: 1,171.1 mi
  • Duration: 7h 1m

What companies run services between Fort Myers, FL, USA and Buffalo, NY, USA?

JetBlue Airways, Southwest Airlines, and two other airlines fly from Ft. Myers (RSW) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a bus from Fort Myers Bus Stop to Buffalo via Orlando Bus Station, New York City Chinatown, and New York Midtown in around 38h 35m.

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