There are 4 ways to get from Fort Myers to Florence by plane, bus (Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Ft. Myers (RSW) to Florence Regional Airport (FLO)plane RSW - FLO
7h 8m$104–478Bus (Flixbus)
- Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus FlixBus 2421
- Take the bus from Orlando Bus Station to Florencebus FlixBus N2472
14h 46m$121–207Bus, train
- Take the bus from Fort Myers Bus Stop to Orlandobus FlixBus 2421
- Take the train from Winter Park Amtrak Station to Florence Stationtrain Silver Meteor
17h 46m$189–383Drive 597.9 mi
- Drive from Fort Myers to Florencecar 597.9 mi
10h 27m$110–158
Fort Myers to Florence by bus and train
Questions & Answers
The cheapest way to get from Fort Myers to Florence is to drive which costs $100 - $160 and takes 10h 27m.
The fastest way to get from Fort Myers to Florence is to fly which takes 7h 8m and costs $100 - $480.
No, there is no direct bus from Fort Myers to Florence. However, there are services departing from Fort Myers Bus Stop and arriving at Florence via Orlando Bus Station. The journey, including transfers, takes approximately 14h 46m.
The distance between Fort Myers and Florence is 564 miles. The road distance is 601.4 miles.
The best way to get from Fort Myers to Florence without a car is to bus which takes 14h 46m and costs $120 - $210.
It takes approximately 7h 8m to get from Fort Myers to Florence, including transfers.
Fort Myers to Florence bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Fort Myers to Florence is to fly which takes 7h 8m and costs $100 - $480. Alternatively, you can bus, which costs $120 - $210 and takes 14h 46m.
Fort Myers to Florence bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Fort Myers to Florence is 601 miles. It takes approximately 10h 27m to drive from Fort Myers to Florence.
What companies run services between Fort Myers, FL, USA and Florence, SC, USA?
American Airlines flies from Ft. Myers (RSW) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Fort Myers Bus Stop to Florence via Orlando Bus Station and Florence in around 14h 46m.
- Website
- aa.com
Flights from Ft. Myers to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $90–460
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Winter Park Amtrak Station to Florence Station
- Ave. Duration
- 9h 29m
- Frequency
- Once daily
- Estimated price
- $150–320
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Fort Myers Bus Stop to Orlando Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Florence
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- $70–130
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
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