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How to get fromFort Myers to Florida Keysby ferry, bus (Flixbus, Greyhound), or car

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There are 3 ways to get from Fort Myers to Florida Keys by ferry, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry

    best
    1. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    6h 21m
    $184–197
  2. Bus

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    9h 15m
    $47–85
  3. Drive 258.4 mi

    1. Drive from Fort Myers to Florida Keyscar car 258.4 mi
    5h 27m
    $48–69

Fort Myers to Florida Keys by bus and foot

Calendar19Weekly Services
Duration9h 15mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

What companies run services between Fort Myers, FL, USA and Florida Keys, FL, USA?

Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from Fort Myers Bus Stop to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 9h 15m.

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