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How to get fromFort Myers to Gainesvilleby bus (Flixbus), car, plane, or bus

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There are 6 ways to get from Fort Myers to Gainesville by bus (Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus FlixBus N2467
    6h 35m
    $39–67

  2. Drive  228.7 mi

    1. Drive from Fort Myers to Gainesvillecar car 228.7 mi
    4h 30m
    $42–61

  3. Fly Ft. Myers to Gainesville Regional Airport

    1. Fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV)plane plane RSW - GNV
    8h 8m
    $96–477

  4. Bus via University

    1. Take the bus from Fort Myers Bus Stop to University of South Floridabus bus FlixBus 2421
    2. Take the bus from University of South Florida - 3801 USF Holly Dr to University of Florida - 1956 Gale Lemerand Drbus bus Miami
    8h
    $52–79

  5. Bus to Miami International Airport, fly to Gainesville Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Gainesville Regional Airport (GNV)plane plane MIA - GNV
    6h 55m
    $71–340

  6. Fly Ft. Myers to Orlando, bus

    1. Fly from Ft. Myers (RSW) to Orlando (MCO)plane plane RSW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 35m
    $384–597

Fort Myers to Gainesville by bus (Flixbus)

Calendar7Weekly Buses
Duration6h 35mAverage Duration
Ticket$39Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Gainesville.ExpandLaunch map view
  • Distance: 265.4 mi
  • Duration: 6h 35m

What companies run services between Fort Myers, FL, USA and Gainesville, FL, USA?

You can take a bus from Fort Myers Bus Stop to Gainesville via Tampa Bus Station in around 6h 35m. Alternatively, Delta and American Airlines fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV) every 4 hours.

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