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How to get fromFort Myers to Gainesvilleby bus (Flixbus), car, plane, or bus

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There are 5 ways to get from Fort Myers to Gainesville by bus (Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Fort Myers

    best
    1. Take the bus from Fort Myers to Tampa USFbus bus Miami–Tampa / ...
    2. Take the bus from University of South Florida to Gainesvillebus bus FlixBus N2467
    5h 29m
    $67–121

  2. Bus

    cheapest
    1. Take the bus from Fort Myers Bus Stop to University of South Floridabus bus FlixBus 2421
    2. Take the bus from University of South Florida to Gainesvillebus bus FlixBus N2467
    6h 20m
    $41–71

  3. Drive 228.7 mi

    1. Drive from Fort Myers to Gainesvillecar car 228.7 mi
    4h 30m
    $42–61

  4. Fly to Gainesville Regional Airport

    1. Fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV)plane plane RSW - GNV
    8h 12m
    $106–497

  5. Fly to Orlando, bus

    1. Fly from Ft. Myers (RSW) to Orlando (MCO)plane plane RSW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 33m
    $314–662

Fort Myers to Gainesville by bus

Calendar7Weekly Buses
Duration6h 20mAverage Duration
Ticket$41Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Gainesville.ExpandLaunch map view
  • Distance: 258.7 mi
  • Duration: 5h 29m

What companies run services between Fort Myers, FL, USA and Gainesville, FL, USA?

You can take a vehicle from Fort Myers to Gainesville via Fort Myers and University of South Florida in around 5h 29m. Alternatively, Delta and American Airlines fly from Ft. Myers (RSW) to Gainesville Regional Airport (GNV) every 4 hours.

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