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How to get fromFort Myers to Greenvilleby bus, plane, bus (Flixbus), car, taxi, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Fort Myers to Greenville by bus, plane, bus (Flixbus), car, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 140 bus to Ft. Myers, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP)plane plane RSW - GSP
    4h 59m
    $168–750

  2. Drive 631.7 mi

    cheapest
    1. Drive from Fort Myers to Greenvillecar car 631.7 mi
    13h 18m
    $116–167

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    18h 10m
    $154–327

  4. Taxi to Punta Gorda Airport, fly to Asheville Regional Airport, taxi

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Asheville Regional Airport (AVL)plane plane PGD - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    3h 22m
    $286–625

  5. Bus to Tampa, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    7h 25m
    $148–413

  6. Bus to Miami International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Greenville–Spartanburg International Airport (GSP)plane plane MIA - GSP
    6h 38m
    $155–635

  7. Bus via Gainesville

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    22h 30m
    $164–358

Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP) flights

Calendar29Weekly Planes
Duration3h 39mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Greenville.ExpandLaunch map view
  • Distance: 605.8 mi
  • Duration: 4h 59m

What companies run services between Fort Myers, FL, USA and Greenville, SC, USA?

You can take a bus from Fort Myers Bus Stop to Greenville via Tampa Bus Station, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 18h 10m.

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