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How to get fromFort Myers to Hyannisby plane, bus (Flixbus), bus, train, or car

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There are 8 ways to get from Fort Myers to Hyannis by plane, bus (Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Barnstable Municipal Airport

    best
    1. Fly from Ft. Myers (RSW) to Barnstable Municipal Airport (HYA)plane plane RSW - HYA
    7h 56m
    $154–755

  2. Fly Ft. Myers to Theodore Francis Green State Airport, train, bus

    cheapest
    1. Fly from Ft. Myers (RSW) to Theodore Francis Green State Airport (PVD)plane plane RSW - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    10h 47m
    $130–476

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    3. Take the bus from NYC Downtown to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    35h 55m
    $260–394

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    37h 19m
    $413–877

  5. Drive  1,461.5 mi

    1. Drive from Fort Myers to Hyanniscar car 1,461.5 mi
    26h 8m
    $267–386

  6. Fly Ft. Myers to Boston Logan Airport, bus

    1. Fly from Ft. Myers (RSW) to Boston Logan Airport (BOS)plane plane RSW - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 39m
    $152–645

  7. Bus to Sarasota–Bradenton International Airport, fly to Boston Logan Airport, bus

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Boston Logan Airport (BOS)plane plane SRQ - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    9h 23m
    $200–859

  8. Fly Ft. Myers to Provincetown Municipal Airport, bus

    1. Fly from Ft. Myers (RSW) to Provincetown Municipal Airport (PVC)plane plane RSW - PVC
    2. Take the bus from Provincetown to Hyannisbus bus
    10h 34m
    $168–692

Fort Myers to Hyannis by bus and foot

Calendar5Weekly Services
Duration35h 55mAverage Duration
Ticket$260Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Hyannis.ExpandLaunch map view
  • Distance: 1,247.3 mi
  • Duration: 7h 56m

What companies run services between Fort Myers, FL, USA and Hyannis, MA, USA?

JetBlue Airways, Cape Air, and Delta fly from Ft. Myers (RSW) to Barnstable Municipal Airport (HYA) twice daily. Alternatively, you can take a bus from Fort Myers Bus Stop to Hyannis Transportation Center via Orlando Bus Station, New York City Chinatown, NYC Downtown, Boston, and Boston South Buses in around 35h 55m.

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