There are 3 ways to get from Fort Myers to Key West, FL by ferry, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
4h 42m$178–187Bus
cheapest- Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus Lks
10h 9m$45–74Drive 275.3 mi
- Drive from Fort Myers to Key West, FLcar 275.3 mi
5h 53m$51–73
Fort Myers to Key West, FL by bus and foot
Comparing Your Travel Options
The cheapest way to get from Fort Myers to Key West, FL is to bus which costs $40 - $75 and takes 10h 9m.
The fastest way to get from Fort Myers to Key West, FL is to ferry which takes 4h 42m and costs $175 - $190.
No, there is no direct bus from Fort Myers to Key West, FL. However, there are services departing from Fort Myers Bus Stop and arriving at Whitehead & Eaton via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 10h 9m.
No, there is no direct ferry from Fort Myers to Key West, FL. However, there are services departing from Fort Myers Beach, FL and arriving at Key West, FL via . The journey, including transfers, takes approximately 4h 42m.
The distance between Fort Myers and Key West, FL is 155 miles. The road distance is 276.9 miles.
The best way to get from Fort Myers to Key West, FL without a car is to ferry which takes 4h 42m and costs $175 - $190.
It takes approximately 4h 42m to get from Fort Myers to Key West, FL, including transfers.
Fort Myers to Key West, FL bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Key West, FL bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Fort Myers to Key West, FL is 277 miles. It takes approximately 5h 53m to drive from Fort Myers to Key West, FL.
What companies run services between Fort Myers, FL, USA and Key West, FL, USA?
Key West Express operates a ferry from Fort Myers Beach, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from Fort Myers Bus Stop to Whitehead & Eaton via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 10h 9m.
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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Booking & Getting There
There are 969+ hotels available in Key West, FL.





