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How to get fromFort Myers to La Crosseby plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

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There are 7 ways to get from Fort Myers to La Crosse by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to La Crosse

    best
    1. Fly from Ft. Myers (RSW) to La Crosse (LSE)plane plane RSW - LSE
    9h 19m
    $162–678

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to La Crossebus bus
    37h 15m
    $275–483

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    2d 3h
    $666–1,431

  4. Drive 1,509.5 mi

    1. Drive from Fort Myers to La Crossecar car 1,509.5 mi
    26h 31m
    $276–398

  5. Fly Ft. Myers to Dane County Regional Airport-Truax Field, bus

    1. Fly from Ft. Myers (RSW) to Dane County Regional Airport-Truax Field (MSN)plane plane RSW - MSN
    2. Take the bus from Madison to UW La Crossebus bus
    10h 19m
    $240–962

  6. Taxi to Punta Gorda Airport, fly to La Crosse

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to La Crosse (LSE)plane plane PGD - LSE
    4h 20m
    $210–618

  7. Fly Ft. Myers to Minneapolis–Saint Paul International Airport, train

    1. Fly from Ft. Myers (RSW) to Minneapolis–Saint Paul International Airport (MSP)plane plane RSW - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    10h 57m
    $226–893

Fort Myers to La Crosse by bus and train

Calendar7Weekly Services
Duration2d 3hAverage Duration
Ticket$666Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to La Crosse.ExpandLaunch map view
  • Distance: 1,333.7 mi
  • Duration: 9h 19m

What companies run services between Fort Myers, FL, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Ft. Myers (RSW) to La Crosse (LSE) 5 times a day. Alternatively, you can take a bus from Fort Myers Bus Stop to La Crosse via Tampa Bus Station, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 37h 15m.

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