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How to get fromFort Myers to Lafayetteby plane, bus (Flixbus, Greyhound), car, or bus

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There are 6 ways to get from Fort Myers to Lafayette by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Lafayette Regional Airport

    best
    1. Fly from Ft. Myers (RSW) to Lafayette Regional Airport (LFT)plane plane RSW - LFT
    7h 43m
    $124–568

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Lafayette Transit Systembus bus
    22h 15m
    $132–256

  3. Drive 859.3 mi

    1. Drive from Fort Myers to Lafayettecar car 859.3 mi
    14h 56m
    $157–227

  4. Bus to Sarasota–Bradenton International Airport, fly to Lafayette Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lafayette Regional Airport (LFT)plane plane SRQ - LFT
    8h 47m
    $134–635

  5. Fly Ft. Myers to Louis Armstrong New Orleans International Airport, bus

    1. Fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY)plane plane RSW - MSY
    2. Take the bus from New Orleans International Airport to Lafayette Transit Systembus bus
    9h 37m
    $274–850

  6. Bus via Oak Ridge

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the bus from Orlando to Tallahasseebus bus
    3. Take the bus from Tallahassee to Lafayette Transit Systembus bus
    24h 55m
    $151–279

Fort Myers to Lafayette by bus

Calendar14Weekly Buses
Duration22h 15mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Lafayette.ExpandLaunch map view
  • Distance: 689.8 mi
  • Duration: 7h 43m

What companies run services between Fort Myers, FL, USA and Lafayette, LA, USA?

Delta, United Airlines, and American Airlines fly from Ft. Myers (RSW) to Lafayette Regional Airport (LFT) every 4 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Lafayette Transit System via Tampa Bus Station and Tallahassee in around 22h 15m.

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