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How to get fromFort Myers to Louisvilleby taxi, plane, car, bus (Flixbus, Greyhound, Amtrak), or bus

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There are 7 ways to get from Fort Myers to Louisville by taxi, plane, car, bus (Flixbus, Greyhound, Amtrak), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Punta Gorda Airport, fly to Blue Grass Airport, drive

    best
    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Blue Grass Airport (LEX)plane plane PGD - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    3h 59m
    $160–516
  2. Bus to Tampa, fly to Louisville International Airport

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Louisville International Airport (SDF)plane plane TPA - SDF
    8h 2m
    $153–785
  3. Bus via Atlanta

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    23h 5m
    $170–279
  4. Drive  928.7 mi

    1. Drive from Fort Myers to Louisvillecar car 928.7 mi
    17h 15m
    $165–238
  5. Fly Ft. Myers to Louisville International Airport

    1. Fly from Ft. Myers (RSW) to Louisville International Airport (SDF)plane plane RSW - SDF
    6h 39m
    $164–858
  6. Taxi to Punta Gorda Airport, fly to Louisville International Airport

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Louisville International Airport (SDF)plane plane PGD - SDF
    4h 3m
    $224–890
  7. Bus

    1. Take the bus from Fort Myers Bus Stop to University of South Floridabus bus
    2. Take the bus from University of South Florida - 3801 USF Holly Dr to Tallahassee, FLbus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    27h 39m
    $210–320

Fort Myers to Louisville by bus

Calendar5Weekly Buses
Duration23h 5mAverage Duration
Ticket$170Cheapest Price
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Comparing Your Travel Options

What companies run services between Fort Myers, FL, USA and Louisville, KY, USA?

You can take a bus from Fort Myers Bus Stop to Louisville, KY via Tampa Bus Station, Atlanta Bus Station, and Nashville in around 23h 5m. Alternatively, Southwest Airlines, Breeze Airways, and two other airlines fly from Ft. Myers (RSW) to Louisville International Airport (SDF) every 4 hours.

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