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How to get fromFort Myers to Mayo Clinic Floridaby bus, plane, taxi, bus (Flixbus), train, or car

Find Transport to Mayo Clinic Florida

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There are 6 ways to get from Fort Myers to Mayo Clinic Florida by bus, plane, taxi, bus (Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly, taxi

    best
    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane plane FLL - JAX
    3. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    5h 11m
    $211–725

  2. Drive 288.4 mi

    cheapest
    1. Drive from Fort Myers to Mayo Clinic Floridacar car 288.4 mi
    5h 24m
    $53–76

  3. Bus (Flixbus)

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus FlixBus 2433 / ...
    10h 14m
    $66–111

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Jacksonvilletrain train Floridian
    10h 35m
    $156–270

  5. Bus to Miami International Airport, fly, taxi

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    3. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    6h 8m
    $145–462

  6. Fly from Ft. Myers, taxi

    1. Fly from Ft. Myers (RSW) to Jacksonville (JAX)plane plane RSW - JAX
    2. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    7h 31m
    $384–895

Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX) flights

Calendar21Weekly Planes
Duration1h 22mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Mayo Clinic Florida.ExpandLaunch map view
  • Distance: 479.6 mi
  • Duration: 5h 11m

What companies run services between Fort Myers, FL, USA and Mayo Clinic Florida, FL, USA?

You can take a bus from Fort Myers Bus Stop to Mayo Clinic Florida via Orlando Bus Station, Jacksonville, JRTC Bay M, and Beach Blvd + Hodges Blvd in around 10h 14m.

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