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How to get fromFort Myers to Mayoby bus, car, plane, taxi, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Fort Myers to Mayo by bus, car, plane, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Fort Myers 7-11 to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Drive from Gainesville to Mayocar car
    6h 55m
    $78–138

  2. Drive 288.1 mi

    cheapest
    1. Drive from Fort Myers to Mayocar car 288.1 mi
    5h 35m
    $53–76

  3. Fly Ft. Myers to Valdosta, drive

    1. Fly from Ft. Myers (RSW) to Valdosta (VLD)plane plane RSW - VLD
    2. Drive from Valdosta (VLD) to Mayocar car
    8h 55m
    $104–492

  4. Bus, taxi

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Perrybus bus
    3. Take the taxi from Perry to Mayotaxi taxi
    9h 2m
    $139–201

  5. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Branfordbus bus Greyhound US0761S
    10h 31m
    $109–172

  6. Bus to Miami International Airport, fly to Tallahassee, bus, taxi

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Tallahassee (TLH)plane plane MIA - TLH
    3. Take the bus from Tallahassee to Perrybus bus
    4. Take the taxi from Perry to Mayotaxi taxi
    8h 33m
    $211–587

Ft. Myers (RSW) to Valdosta (VLD) flights

Calendar21Weekly Planes
Duration5h 4mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Mayo.ExpandLaunch map view
  • Distance: 323.9 mi
  • Duration: 6h 55m

What companies run services between Fort Myers, FL, USA and Mayo, FL, USA?

You can take a bus from Fort Myers Bus Stop to Mayo via Orlando Bus Station and Branford in around 10h 31m.

Airlines
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