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How to get fromFort Myers to Mississippiby plane, bus (Flixbus, Greyhound), car, or bus

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There are 7 ways to get from Fort Myers to Mississippi by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT)plane plane RSW - GPT
    7h 41m
    $134–619

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonbus bus
    20h 50m
    $155–283

  3. Drive 790.5 mi

    1. Drive from Fort Myers to Jacksoncar car 790.5 mi
    14h 9m
    $145–209

  4. Bus to Tampa, fly to Memphis

    1. Take the bus from Fort Myers to Tampa Airportbus bus
    2. Fly from Tampa (TPA) to Memphis (MEM)plane plane TPA - MEM
    5h 51m
    $200–813

  5. Fly Ft. Myers to Memphis

    1. Fly from Ft. Myers (RSW) to Memphis (MEM)plane plane RSW - MEM
    7h 7m
    $196–882

  6. Fly Ft. Myers to Jackson/Vicksburg

    1. Fly from Ft. Myers (RSW) to Jackson/Vicksburg (JAN)plane plane RSW - JAN
    7h 12m
    $134–515

  7. Bus via Orlando

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonbus bus
    23h 26m
    $212–395

Fort Myers to Mississippi by bus

Calendar7Weekly Buses
Duration20h 50mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Mississippi.ExpandLaunch map view
  • Distance: 537.4 mi
  • Duration: 7h 41m

What companies run services between Fort Myers, FL, USA and Mississippi, USA?

Delta, American Airlines, and Sun Country Airlines fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Jackson via Tampa Bus Station and Atlanta Bus Station in around 20h 50m.

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