There are 6 ways to get from Fort Myers to Mississippi by plane, bus (Flixbus, Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gulfport-Biloxi Regional Airport
best- Fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT)plane RSW - GPT
7h 48m$100–459Bus
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Jacksonbus
21h 50m$170–269Drive 790.5 mi
- Drive from Fort Myers to Jacksoncar 790.5 mi
14h 9m$136–196Fly to Memphis
- Fly from Ft. Myers (RSW) to Memphis (MEM)plane RSW - MEM
7h 7m$186–932Fly to Jackson/Vicksburg
- Fly from Ft. Myers (RSW) to Jackson/Vicksburg (JAN)plane RSW - JAN
7h 17m$128–495Fly to Louis Armstrong New Orleans International Airport, train
- Fly from Ft. Myers (RSW) to Louis Armstrong New Orleans International Airport (MSY)plane RSW - MSY
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
8h 23m$142–620
Fort Myers to Mississippi by bus
Comparing Your Travel Options
The cheapest way to get from Fort Myers to Mississippi is to drive which costs $130 - $200 and takes 14h 9m.
The fastest way to get from Fort Myers to Mississippi is to fly which takes 7h 7m and costs $180 - $950.
No, there is no direct bus from Fort Myers to Mississippi. However, there are services departing from Fort Myers Bus Stop and arriving at Jackson via Tampa Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 21h 50m.
The distance between Fort Myers and Mississippi is 540 miles. The road distance is 795.1 miles.
The best way to get from Fort Myers to Mississippi without a car is to bus which takes 21h 50m and costs $170 - $270.
It takes approximately 7h 48m to get from Fort Myers to Mississippi, including transfers.
Fort Myers to Mississippi bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
The best way to get from Fort Myers to Mississippi is to fly which takes 7h 48m and costs $95 - $460. Alternatively, you can bus, which costs $170 - $270 and takes 21h 50m.
Fort Myers to Mississippi bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
Mississippi is 1h behind Fort Myers. It is currently 8:36 PM in Fort Myers and 7:36 PM in Mississippi.
What companies run services between Fort Myers, FL, USA and Mississippi, USA?
Delta, American Airlines, and United Airlines fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Jackson via Tampa Bus Station and Atlanta Bus Station in around 21h 50m.
- Website
- delta.com
Flights from Ft. Myers to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $85–440
Flights from Ft. Myers to Memphis via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $170–900
Flights from Ft. Myers to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $85–440
Flights from Ft. Myers to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–650
- Website
- aa.com
Flights from Ft. Myers to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $100–500
Flights from Ft. Myers to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $120–600
Flights from Ft. Myers to Memphis via Charlotte
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Ft. Myers to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $100–500
Flights from Ft. Myers to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $120–550
Flights from Ft. Myers to Jackson/Vicksburg via Reagan Washington
- Ave. Duration
- 8h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–600
- Website
- southwest.com
Flights from Ft. Myers to Memphis via Orlando
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $160–900
Flights from Ft. Myers to Memphis via Nashville
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $180–900
Flights from Ft. Myers to Jackson/Vicksburg via Nashville
- Ave. Duration
- 6h 30m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $95–470
Flights from Ft. Myers to Louis Armstrong New Orleans International Airport via Orlando
- Ave. Duration
- 3h 55m
- When
- Tuesday and Wednesday
- Estimated price
- $100–550
Flights from Ft. Myers to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $140–700
- Website
- united.com
Flights from Ft. Myers to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $100–550
Flights from Ft. Myers to Memphis via Houston
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Ft. Myers to Jackson/Vicksburg via Houston
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $100–500
- Website
- flybreeze.com
Flights from Ft. Myers to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 3m
- When
- Wednesday and Saturday
- Estimated price
- $200–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $19–30
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Atlanta Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Jackson
- Ave. Duration
- 7h 40m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between Fort Myers to Mississippi is 795 miles. It takes approximately 14h 9m to drive from Fort Myers to Mississippi.
Book your Fort Myers to Mississippi bus tickets online with Omio and FlixBus.
There are 210+ hotels available in Mississippi.






