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How to get fromFort Myers to Mobileby plane, bus (Flixbus, Greyhound), car, or bus

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There are 6 ways to get from Fort Myers to Mobile by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Mobile Regional Airport

    best
    1. Fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB)plane plane RSW - MOB
    7h 19m
    $118–505

  2. Fly Ft. Myers to Pensacola International Airport, bus

    cheapest
    1. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    11h 5m
    $64–342

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    17h 40m
    $107–167

  4. Drive  605.7 mi

    1. Drive from Fort Myers to Mobilecar car 605.7 mi
    10h 46m
    $111–160

  5. Bus to Miami International Airport, fly to Pensacola International Airport, bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    3. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 30m
    $76–314

  6. Bus to Fort Lauderdale–Hollywood International Airport, fly to Pensacola International Airport, bus

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Pensacola International Airport (PNS)plane plane FLL - PNS
    3. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h 52m
    $172–338

Fort Myers to Mobile by bus

Calendar14Weekly Buses
Duration17h 40mAverage Duration
Ticket$107Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Mobile.ExpandLaunch map view
  • Distance: 515.4 mi
  • Duration: 7h 19m

What companies run services between Fort Myers, FL, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Govt EB at Franklin St via Tampa Bus Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 17h 40m.

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