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How to get fromFort Myers to Mobileby plane, bus (Flixbus, Greyhound), car, or bus

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There are 6 ways to get from Fort Myers to Mobile by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Mobile Regional Airport

    best
    1. Fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB)plane plane RSW - MOB
    7h 30m
    $124–525

  2. Fly Ft. Myers to Pensacola International Airport, bus

    cheapest
    1. Fly from Ft. Myers (RSW) to Pensacola International Airport (PNS)plane plane RSW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    10h 36m
    $82–400

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    17h 40m
    $95–155

  4. Drive  605.7 mi

    1. Drive from Fort Myers to Mobilecar car 605.7 mi
    10h 46m
    $111–160

  5. Bus to Sarasota–Bradenton International Airport, fly to Mobile Regional Airport

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Mobile Regional Airport (MOB)plane plane SRQ - MOB
    9h 18m
    $152–709

  6. Fly Ft. Myers to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Ft. Myers (RSW) to Gulfport-Biloxi Regional Airport (GPT)plane plane RSW - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    9h 55m
    $166–686

Fort Myers to Mobile by bus

Calendar14Weekly Buses
Duration17h 40mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Mobile.ExpandLaunch map view
  • Distance: 515.4 mi
  • Duration: 7h 30m

What companies run services between Fort Myers, FL, USA and Mobile, AL, USA?

Delta, United Airlines, and American Airlines fly from Ft. Myers (RSW) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Govt EB at Franklin St via Tampa Bus Station, Tallahassee, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 17h 40m.

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