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How to get fromFort Myers to Myrtle Beachby bus, plane, train, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Fort Myers to Myrtle Beach by bus, plane, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach

    best
    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane plane FLL - MYR
    5h 17m
    $162–509

  2. Bus to Tampa, fly to Myrtle Beach

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    6h 28m
    $113–600

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the train from Winter Park Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    19h 4m
    $197–374

  4. Drive 622.5 mi

    1. Drive from Fort Myers to Myrtle Beachcar car 622.5 mi
    11h 40m
    $114–165

  5. Fly Ft. Myers to Myrtle Beach

    1. Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane plane RSW - MYR
    7h 6m
    $354–619

  6. Fly Ft. Myers to Wilmington International Airport, bus

    1. Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)plane plane RSW - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 35m
    $260–597

  7. Bus

    1. Take the bus from Fort Myers to Miamibus bus
    2. Take the bus from Miami to Savannah Bus Stationbus bus
    3. Take the bus from Savannah Bus Station to Charleston Bus Stationbus bus
    4. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    21h 36m
    $167–272

Fort Myers to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration19h 4mAverage Duration
Ticket$197Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Myrtle Beach.ExpandLaunch map view
  • Distance: 667 mi
  • Duration: 5h 17m

What companies run services between Fort Myers, FL, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Fort Myers to Myrtle Beach Bus Station via Miami, Savannah Bus Station, and Charleston Bus Station in around 21h 36m.

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