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How to get fromFort Myers to Myrtle Beachby bus, plane, train, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Fort Myers to Myrtle Beach by bus, plane, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach

    best
    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane plane FLL - MYR
    5h 16m
    $171–453

  2. Fly Ft. Myers to Myrtle Beach

    cheapest
    1. Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane plane RSW - MYR
    7h 32m
    $90–449

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the train from Winter Park Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    18h 39m
    $146–307

  4. Drive  622.5 mi

    1. Drive from Fort Myers to Myrtle Beachcar car 622.5 mi
    11h 40m
    $114–165

  5. Bus to Tampa, fly to Myrtle Beach

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Myrtle Beach (MYR)plane plane TPA - MYR
    7h 10m
    $123–387

  6. Bus to Orlando, fly to Myrtle Beach

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Fly from Orlando (MCO) to Myrtle Beach (MYR)plane plane MCO - MYR
    9h 12m
    $147–276

  7. Fly Ft. Myers to Wilmington International Airport, bus

    1. Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)plane plane RSW - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 40m
    $130–642

  8. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    20h 15m
    $136–208

Fort Myers to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration18h 39mAverage Duration
Ticket$146Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Myrtle Beach.ExpandLaunch map view
  • Distance: 667 mi
  • Duration: 5h 16m

What companies run services between Fort Myers, FL, USA and Myrtle Beach, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to Myrtle Beach Bus Station via Orlando Bus Station and Fayetteville Bus Station in around 20h 15m.

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