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How to get fromFort Myers to North Charlestonby bus, plane, train, or car

Find Transport to North Charleston

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There are 7 ways to get from Fort Myers to North Charleston by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 140 bus to Ft. Myers, fly

    best
    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    5h 34m
    $106–507

  2. Drive 528.8 mi

    cheapest
    1. Drive from Fort Myers to North Charlestoncar car 528.8 mi
    9h 32m
    $97–140

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus FlixBus 2421
    2. Take the train from Winter Park Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    15h 49m
    $159–323

  4. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    6h 4m
    $194–1,138

  5. Bus to Miami International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    7h 2m
    $528–1,045

  6. Bus to Tampa, fly

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    8h
    $166–381

  7. Bus to Orlando, fly

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    10h 2m
    $106–315

Fort Myers to North Charleston by bus and train

Calendar7Weekly Services
Duration15h 49mAverage Duration
Ticket$159Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to North Charleston.ExpandLaunch map view
  • Distance: 473.5 mi
  • Duration: 5h 34m

What companies run services between Fort Myers, FL, USA and North Charleston, SC, USA?

There is no direct connection from Fort Myers to North Charleston. However, you can take the line 140 bus to South Fort Myers Transfer/P&R, take the line 50 bus to Rsw, walk to Ft. Myers (RSW) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Rivers Ave / Cosgrove Ave. Alternatively, you can take a bus from Fort Myers Bus Stop to Charleston Amtrak Station via Orlando, Florida Mall, N Garland Ave & W Amelia St, New York Ave & Welbourne Ave, and Winter Park Amtrak Station in around 15h 49m.

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