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How to get fromFort Myers to Orlandoby bus (Flixbus), car, bus, plane, or train

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There are 7 ways to get from Fort Myers to Orlando by bus (Flixbus), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    5h 10m
    $35–60

  2. Drive 152 mi

    cheapest
    1. Drive from Fort Myers to Orlandocar car 152 mi
    3h 6m
    $28–41

  3. Line 140 bus to Ft. Myers, fly

    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Orlando (MCO)plane plane RSW - MCO
    4h 13m
    $286–607

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus FlixBus 2421
    2. Take the train from Tampa to Orlandotrain train Floridian
    5h 38m
    $53–97

  5. Bus via Mccoy Rd & Central Ave

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus FlixBus 2421
    6h 22m
    $61–84

  6. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Orlando (MCO)plane plane SRQ - MCO
    5h 2m
    $285–724

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Orlando (MCO)plane plane FLL - MCO
    4h 47m
    $274–637

Fort Myers to Orlando by bus

Calendar42Weekly Buses
Duration5h 10mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Orlando.ExpandLaunch map view
  • Distance: 217.9 mi
  • Duration: 5h 10m

What companies run services between Fort Myers, FL, USA and Orlando, FL, USA?

Jefferson Lines operates a bus from Fort Myers Bus Stop to Orlando Bus Station 3 times a day. Tickets cost $55–80 and the journey takes 5h 10m. Flixbus USA also services this route 3 times a day.

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