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How to get fromFort Myers to Roanokeby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 7 ways to get from Fort Myers to Roanoke by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Ft. Myers (RSW) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane RSW - ROA
    8h 57m
    $92–480

  2. Bus via Charlotte

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Lynchburg Transit Centerbus bus
    4. Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus bus
    24h 39m
    $150–236

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the train from Greensboro to Lynchburgtrain train
    5. Take the train from Lynchburg to Roanoketrain train
    27h 58m
    $250–599

  4. Drive  833.7 mi

    1. Drive from Fort Myers to Roanokecar car 833.7 mi
    15h 12m
    $153–220

  5. Bus to Sarasota–Bradenton International Airport, fly to Roanoke Regional Airport-Woodrum Field

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane SRQ - ROA
    9h 20m
    $126–624

  6. Fly Ft. Myers to Lynchburg Regional Airport, train

    1. Fly from Ft. Myers (RSW) to Lynchburg Regional Airport (LYH)plane plane RSW - LYH
    2. Take the train from Lynchburg to Roanoketrain train
    12h 40m
    $102–512

  7. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Richmondbus bus
    3. Take the bus from Richmond to Lynchburg Transit Centerbus bus
    4. Take the bus from Lynchburg Transit Center to Roanoke Bus Stopbus bus
    26h 39m
    $170–261

Fort Myers to Roanoke by bus

Calendar4Weekly Buses
Duration24h 39mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Roanoke.ExpandLaunch map view
  • Distance: 775.4 mi
  • Duration: 8h 57m

What companies run services between Fort Myers, FL, USA and Roanoke, VA, USA?

Delta, American Airlines, and United Airlines fly from Ft. Myers (RSW) to Roanoke Regional Airport-Woodrum Field (ROA) hourly. Alternatively, you can take a bus from Fort Myers Bus Stop to Roanoke Bus Stop via Orlando Bus Station, Charlotte Bus Station, and Lynchburg Transit Center in around 24h 39m.

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