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How to get fromFort Myers to San Antonioby plane, bus (Flixbus, Greyhound), car, or bus

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There are 8 ways to get from Fort Myers to San Antonio by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ft. Myers to San Antonio International Airport

    best
    1. Fly from Ft. Myers (RSW) to San Antonio International Airport (SAT)plane plane RSW - SAT
    8h 41m
    $166–757

  2. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    31h 5m
    $196–376

  3. Drive 1,265.8 mi

    1. Drive from Fort Myers to San Antoniocar car 1,265.8 mi
    21h 29m
    $231–334

  4. Bus to Tampa, fly to San Antonio International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to San Antonio International Airport (SAT)plane plane TPA - SAT
    8h 51m
    $276–1,341

  5. Bus to Miami International Airport, fly to San Antonio International Airport

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to San Antonio International Airport (SAT)plane plane MIA - SAT
    8h
    $627–944

  6. Fly Ft. Myers to Austin-Bergstrom International Airport, bus

    1. Fly from Ft. Myers (RSW) to Austin-Bergstrom International Airport (AUS)plane plane RSW - AUS
    2. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    10h 35m
    $166–782

  7. Bus to Tampa, fly to Austin-Bergstrom International Airport, bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Austin-Bergstrom International Airport (AUS)plane plane TPA - AUS
    3. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    11h
    $217–866

  8. Bus via Oak Ridge

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Take the bus from Orlando to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Hyatt Regency Galleria Houston to San Antoniobus bus
    34h 33m
    $318–493

Fort Myers to San Antonio by bus

Calendar14Weekly Buses
Duration31h 5mAverage Duration
Ticket$196Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to San Antonio.ExpandLaunch map view
  • Distance: 1,063.2 mi
  • Duration: 8h 41m

What companies run services between Fort Myers, FL, USA and San Antonio, TX, USA?

American Airlines, United Airlines, and two other airlines fly from Ft. Myers (RSW) to San Antonio International Airport (SAT) every 2 hours. Alternatively, you can take a bus from Fort Myers Bus Stop to San Antonio Bus Station via Tampa Bus Station, Tallahassee, and Houston Bus Station in around 31h 5m.

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