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How to get fromFort Myers to San Diegoby plane, bus (Flixbus, Greyhound, Amtrak), bus, train, or car

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There are 8 ways to get from Fort Myers to San Diego by plane, bus (Flixbus, Greyhound, Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ft. Myers

    best
    1. Fly from Ft. Myers (RSW) to San Diego International Airport (SAN)plane plane RSW - SAN
    9h 46m
    $224–905

  2. Bus to Miami International Airport, fly

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Fly from Miami International Airport (MIA) to San Diego International Airport (SAN)plane plane MIA - SAN
    9h 28m
    $165–522

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles to San Diegobus bus
    2d 18h
    $462–876

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 20h
    $1,306–2,810

  5. Drive 2,520.2 mi

    1. Drive from Fort Myers to San Diegocar car 2,520.2 mi
    41h 9m
    $460–665

  6. Bus to Tampa, fly

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to San Diego International Airport (SAN)plane plane TPA - SAN
    10h 20m
    $214–789

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to San Diego International Airport (SAN)plane plane FLL - SAN
    8h 55m
    $311–1,235

  8. Bus to Orlando, fly

    1. Take the bus from Fort Myers Bus Stop to Orlandobus bus
    2. Fly from Orlando (MCO) to San Diego International Airport (SAN)plane plane MCO - SAN
    12h 36m
    $258–1,012

Fort Myers to San Diego by bus and foot

Calendar7Weekly Services
Duration2d 18hAverage Duration
Ticket$462Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to San Diego.ExpandLaunch map view
  • Distance: 2,176 mi
  • Duration: 9h 46m

What companies run services between Fort Myers, FL, USA and San Diego, CA, USA?

American Airlines, United Airlines, and Southwest Airlines fly from Ft. Myers (RSW) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a bus from Fort Myers Bus Stop to San Diego via Tampa Bus Station, Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 18h.

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