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How to get fromFort Myers to Sioux Fallsby plane, bus, train, car, or taxi

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There are 7 ways to get from Fort Myers to Sioux Falls by plane, bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Ft. Myers

    best
    1. Fly from Ft. Myers (RSW) to Sioux Falls (FSD)plane plane RSW - FSD
    10h 20m
    $126–557

  2. Bus to Tampa, fly

    cheapest
    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Sioux Falls (FSD)plane plane TPA - FSD
    11h 1m
    $124–515

  3. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from Minneapolis to Sioux Fallsbus bus
    2d 13h
    $1,274–2,103

  4. Drive  1,666.9 mi

    1. Drive from Fort Myers to Sioux Fallscar car 1,666.9 mi
    29h 44m
    $285–412

  5. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Sioux Falls (FSD)plane plane SRQ - FSD
    10h 41m
    $125–573

  6. Taxi to Punta Gorda Airport, fly

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Sioux Falls (FSD)plane plane PGD - FSD
    5h 44m
    $185–639

  7. Bus, train via Kansas City

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    4. Take the bus from Kansas City to Sioux Fallsbus bus
    2d 16h
    $1,319–2,157

Ft. Myers (RSW) to Sioux Falls (FSD) flights

Calendar101Weekly Planes
Duration7h 31mAverage Duration
Ticket$121Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Sioux Falls.ExpandLaunch map view
  • Distance: 1,467.1 mi
  • Duration: 10h 20m

What companies run services between Fort Myers, FL, USA and Sioux Falls, SD, USA?

Delta, United Airlines, and American Airlines fly from Ft. Myers (RSW) to Sioux Falls (FSD) hourly.

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