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How to get fromFort Myers to South Carolinaby bus, plane, train, taxi, or car

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There are 12 ways to get from Fort Myers to South Carolina by bus, plane, train, taxi, or car

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  1. Line 140 bus to Ft. Myers, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP)plane plane RSW - GSP
    4h 59m
    $168–750

  2. Drive 529.3 mi

    cheapest
    1. Drive from Fort Myers to Charlestoncar car 529.3 mi
    9h 35m
    $97–140

  3. Bus, train, taxi, drive

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Trolley Stop 10 - Coligny Beach Parktaxi taxi
    4. Drive from Trolley Stop 1 - Shelter Cove Towne Centre to Charlestoncar car
    16h 46m
    $325–528

  4. Bus, Amtrak Thruway, train, taxi

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Union Station to Orlando, FLbus bus
    3. Take the train from Orlando to Savannah Stationtrain train
    4. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    5. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    6. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    20h 30m

  5. Taxi to Punta Gorda Airport, fly to Asheville Regional Airport, taxi

    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Asheville Regional Airport (AVL)plane plane PGD - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    3h 22m
    $286–625

  6. Fly Ft. Myers to Charlotte Douglas International Airport, taxi

    1. Fly from Ft. Myers (RSW) to Charlotte Douglas International Airport (CLT)plane plane RSW - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 32m
    $204–755

  7. Line 140 bus to Ft. Myers, fly to Charleston International Airport

    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    5h 34m
    $106–507

  8. Bus to Sarasota–Bradenton International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Charlotte Douglas International Airport (CLT)plane plane SRQ - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    6h 30m
    $213–822

  9. Bus to Tampa, fly to Charleston International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    8h
    $166–381

  10. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus FlixBus 2421
    2. Take the train from Fort Lauderdale Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    17h 27m
    $254–502

  11. Bus, Amtrak Thruway, train

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Take the bus from Sarasota Amtrak Bus Stop to Orlando, FLbus bus
    3. Take the train from Orlando to Charleston Amtrak Stationtrain train
    18h 26m
    $187–369

  12. Bus, train, taxi

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    5. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    19h 8m

Fort Myers to South Carolina by bus and train

Calendar7Weekly Services
Duration18h 26mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to South Carolina.ExpandLaunch map view
  • Distance: 605.8 mi
  • Duration: 4h 59m

What companies run services between Fort Myers, FL, USA and South Carolina, USA?

There is no direct connection from Fort Myers to South Carolina. However, you can take the line 140 bus to South Fort Myers Transfer/P&R, take the line 50 bus to Rsw, walk to Ft. Myers (RSW) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Greenville. Alternatively, you can take the bus to Tampa Bus Station, walk to Marion Transit Center, take the line 400 bus to Nebraska Av @ Twiggs St, walk to Tampa, take the train to Savannah Station, take the taxi to Trolley Stop 10 - Coligny Beach Park, take the line 505 bus to Trolley Stop 1 - Shelter Cove Towne Centre, then drive to Charleston.

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