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How to get fromFort Myers to Spartanburgby taxi, plane, car, bus (Flixbus, Greyhound), bus, or train

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There are 7 ways to get from Fort Myers to Spartanburg by taxi, plane, car, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Punta Gorda Airport, fly to Asheville Regional Airport, drive

    best
    1. Take the taxi from Fort Myers to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Asheville Regional Airport (AVL)plane plane PGD - AVL
    3. Drive from Asheville-Airport-AVL to Spartanburgcar car
    3h 24m
    $155–470

  2. Drive 668.3 mi

    cheapest
    1. Drive from Fort Myers to Spartanburgcar car 668.3 mi
    11h 37m
    $122–177

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Spartanburgbus bus
    18h 48m
    $149–254

  4. Bus, train

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Take the train from Tampa to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    26h 37m
    $330–686

  5. Line 140 bus to Ft. Myers, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Edison Mall Transfer Ctr to South Fort Myers Transfer/P&Rbus bus
    2. Fly from Ft. Myers (RSW) to Greenville–Spartanburg International Airport (GSP)plane plane RSW - GSP
    5h 8m
    $188–775

  6. Bus to Tampa, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    7h 34m
    $169–440

  7. Bus via Atlanta

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus
    2. Take the bus from Hollywood Sheridan Trirail Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Servicios Zapata - Spartanburgbus bus
    25h 11m
    $187–405

Fort Myers to Spartanburg by bus and train

Calendar7Weekly Services
Duration26h 37mAverage Duration
Ticket$330Cheapest Price
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Questions & Answers

Map of how to get from Fort Myers to Spartanburg.ExpandLaunch map view
  • Distance: 668.7 mi
  • Duration: 3h 24m

What companies run services between Fort Myers, FL, USA and Spartanburg, SC, USA?

You can take a bus from Fort Myers Bus Stop to Spartanburg via Orlando Bus Station, Charlotte Bus Station, and Spartanburg in around 18h 48m.

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