There are 5 ways to get from Fort Myers to Tupelo by plane, car, bus (Flixbus, Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Ft. Myers to Golden Triangle Regional Airport, drive
best- Fly from Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR)plane RSW - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
8h 9m$100–482Bus
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tupelobus
19h 39m$136–224Drive 763.1 mi
- Drive from Fort Myers to Tupelocar 763.1 mi
14h 12m$140–202Bus to Tampa, fly to Birmingham–Shuttlesworth International Airport, drive
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Birmingham–Shuttlesworth International Airport (BHM)plane TPA - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
9h 16m$156–723Fly Ft. Myers to Memphis, bus
- Fly from Ft. Myers (RSW) to Memphis (MEM)plane RSW - MEM
- Take the bus from Memphis Bus Station to Tupelobus
11h 7m$190–945
Ft. Myers (RSW) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Fort Myers to Tupelo is to bus which costs $130 - $230 and takes 19h 39m.
The fastest way to get from Fort Myers to Tupelo is to fly and drive which takes 8h 9m and costs $95 - $490.
No, there is no direct bus from Fort Myers to Tupelo. However, there are services departing from Fort Myers Bus Stop and arriving at Tupelo via Tampa Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 19h 39m.
The distance between Fort Myers and Tupelo is 710 miles. The road distance is 767.6 miles.
The best way to get from Fort Myers to Tupelo without a car is to bus which takes 19h 39m and costs $130 - $230.
It takes approximately 8h 9m to get from Fort Myers to Tupelo, including transfers.
Fort Myers to Tupelo bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Tupelo bus services, operated by Flixbus USA, arrive at Tampa Bus Station.
Tupelo is 1h behind Fort Myers. It is currently 1:04 AM in Fort Myers and 12:04 AM in Tupelo.
Yes, the driving distance between Fort Myers to Tupelo is 768 miles. It takes approximately 14h 12m to drive from Fort Myers to Tupelo.
What companies run services between Fort Myers, FL, USA and Tupelo, MS, USA?
You can take a bus from Fort Myers Bus Stop to Tupelo via Tampa Bus Station, Atlanta Bus Station, and Tupelo in around 19h 39m.
- Website
- delta.com
Flights from Ft. Myers to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $85–460
Flights from Tampa to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $120–700
Flights from Ft. Myers to Memphis via Atlanta
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $170–900
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Book your Fort Myers to Tupelo bus tickets online with Omio.
There are 33+ hotels available in Tupelo.