There are 4 ways to get from Fort Pierce to Florence by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Vero Beach Municipal Airport (VRB) to Florence Regional Airport (FLO)plane VRB - FLO
7h 39m$134–463Drive 531 mi
cheapest- Drive from Fort Pierce to Florencecar 531 mi
8h 41m$94–136Bus
- Take the bus from Fort Pierce to Jacksonvillebus Greyhound US0710s
- Take the bus from Jacksonville to Florencebus FlixBus N2472
13h 24m$108–157Bus, train
- Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus Miami
- Take the train from Kissimmee Amtrak Station to Florence Stationtrain Silver Meteor
15h 39m$306–475
Fort Pierce to Florence by bus and train
Comparing Your Travel Options
The cheapest way to get from Fort Pierce to Florence is to drive which costs $90 - $140 and takes 8h 41m.
The fastest way to get from Fort Pierce to Florence is to fly which takes 7h 39m and costs $130 - $470.
No, there is no direct bus from Fort Pierce to Florence. However, there are services departing from Orange Ave & N 9th St and arriving at Florence via Fort Pierce and Jacksonville. The journey, including transfers, takes approximately 13h 24m.
The distance between Fort Pierce and Florence is 475 miles. The road distance is 534.1 miles.
The best way to get from Fort Pierce to Florence without a car is to bus which takes 13h 24m and costs $100 - $160.
It takes approximately 7h 39m to get from Fort Pierce to Florence, including transfers.
Fort Pierce to Florence bus services, operated by Greyhound USA, depart from Fort Pierce station.
The best way to get from Fort Pierce to Florence is to fly which takes 7h 39m and costs $130 - $470. Alternatively, you can bus, which costs $100 - $160 and takes 13h 24m.
Fort Pierce to Florence bus services, operated by Greyhound USA, arrive at Jacksonville station.
Yes, the driving distance between Fort Pierce to Florence is 534 miles. It takes approximately 8h 41m to drive from Fort Pierce to Florence.
What companies run services between Fort Pierce, FL, USA and Florence, SC, USA?
American Airlines and Breeze Airways fly from Vero Beach Municipal Airport (VRB) to Florence Regional Airport (FLO) once daily. Alternatively, you can take a bus from Orange Ave & N 9th St to Florence via Wheeler Ter & Okeechobee Rd, Fort Pierce, Jacksonville, and Florence in around 13h 24m.
- Website
- aa.com
Flights from Vero Beach Municipal Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 9h 23m
- When
- Every day
- Estimated price
- $65–380
Flights from Vero Beach Municipal Airport to Florence Regional Airport via Philadelphia, Charlotte
- Ave. Duration
- 10h 14m
- When
- Saturday
- Estimated price
- $110–550
Flights from Vero Beach Municipal Airport to Florence Regional Airport via Raleigh/Durham, Charlotte
- Ave. Duration
- 7h 10m
- When
- Monday
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kissimmee Amtrak Station to Florence Station
- Ave. Duration
- 10h 25m
- Frequency
- Once daily
- Estimated price
- $280–440
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Fort Pierce to Jacksonville
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Florence
- Ave. Duration
- 5h 35m
- Frequency
- 5 times a week
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Fort Pierce to Kissimmee -1471 East Osceola Parkway
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $24–35
- Website
- RedCoach
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Booking & Getting There
Book your Fort Pierce to Florence bus tickets online with Omio.
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