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How to get fromFort Pierce to Great Smoky Mountainsby car, plane, bus, train, shuttle, or taxi

Find Transport to Great Smoky Mountains

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There are 10 ways to get from Fort Pierce to Great Smoky Mountains by car, plane, bus, train, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport, drive

    best
    1. Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 49m
    $142–698

  2. Drive to Orlando Sanford, fly to Asheville Regional Airport, drive

    cheapest
    1. Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    5h 59m
    $91–394

  3. Bus, drive

    1. Take the bus from Fort Pierce to Orlando - RedCoach Station, FLbus bus
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 51m
    $171–316

  4. Bus, train, drive

    1. Take the bus from Fort Pierce to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the train from Kissimmee Amtrak Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    28h 7m
    $288–597

  5. Drive 670.6 mi

    1. Drive from Fort Pierce to Great Smoky Mountainscar car 670.6 mi
    13h 50m
    $123–177

  6. Shuttle to Orlando, fly to Mcghee Tyson Airport, drive

    1. Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 51m
    $183–699

  7. Bus to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)plane plane FLL - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 58m
    $166–764

  8. Bus to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane plane FLL - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    8h 8m
    $110–450

  9. Bus to President Donald J. Trump International Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Fort Pierce to West Palm Beach, FLbus bus
    2. Fly from President Donald J. Trump International Airport (PBI) to Asheville Regional Airport (AVL)plane plane PBI - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    8h 22m
    $99–470

  10. Bus, taxi to Melbourne International Airport, fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Take the bus from Fort Pierce to Sebastianbus bus
    2. Take the taxi from Sebastian to Melbourne International Airport (MLB)taxi taxi
    3. Fly from Melbourne International Airport (MLB) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MLB - ATL
    4. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    9h 16m
    $200–614

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar10Weekly Planes
Duration1h 38mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Fort Pierce to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 693.5 mi
  • Duration: 5h 49m

What companies run services between Fort Pierce, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Fort Pierce to Great Smoky Mountains. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Orange Ave & N 9th St to Great Smoky Mountains via Wheeler Ter & Okeechobee Rd, Fort Pierce, Mccoy Rd & Gondola Dr, N Garland Ave & W Amelia St, N John Young Pkwy & Business Center Blvd, Orlando Bus Station, Raleigh Bus Station, and Asheville, NC in around 24h 51m.

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