Rome2Rio

How to get fromFort Pierce to San Diegoby plane, bus (Flixbus, Greyhound, Amtrak), bus, train, car, shuttle, or taxi

Find Transport to San Diego

See all options

There are 8 ways to get from Fort Pierce to San Diego by plane, bus (Flixbus, Greyhound, Amtrak), bus, train, car, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Vero Beach Municipal Airport

    best
    1. Fly from Vero Beach Municipal Airport (VRB) to San Diego International Airport (SAN)plane plane VRB - SAN
    8h 53m
    $229–770
  2. Bus to Miami International Airport, fly

    cheapest
    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to San Diego International Airport (SAN)plane plane MIA - SAN
    10h 5m
    $152–504
  3. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 19h
  4. Bus, train

    1. Take the bus from Fort Pierce to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 23h
    $2,365–3,709
  5. Drive  2,527.8 mi

    1. Drive from Fort Pierce to San Diegocar car 2,527.8 mi
    39h 47m
    $447–646
  6. Shuttle to Orlando, fly

    1. Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to San Diego International Airport (SAN)plane plane MCO - SAN
    9h 35m
    $293–523
  7. Bus, taxi to Melbourne International Airport, fly

    1. Take the bus from Fort Pierce to Sebastianbus bus
    2. Take the taxi from Sebastian to Melbourne International Airport (MLB)taxi taxi
    3. Fly from Melbourne International Airport (MLB) to San Diego International Airport (SAN)plane plane MLB - SAN
    11h 41m
    $240–768
  8. Bus to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to San Diego International Airport (SAN)plane plane FLL - SAN
    9h 38m
    $346–1,035

Vero Beach Municipal Airport (VRB) to San Diego International Airport (SAN) flights

Calendar17Weekly Planes
Duration10h 7mAverage Duration
Ticket$173Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Fort Pierce, FL, USA and San Diego, CA, USA?

American Airlines, Breeze Airways, and two other airlines fly from Vero Beach Municipal Airport (VRB) to San Diego International Airport (SAN) twice daily. Alternatively, you can take a bus from Orange Ave & N 9th St to San Diego via Wheeler Ter & Okeechobee Rd, Fort Pierce, Port St Lucie, Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 19h.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There