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How to get fromFort Pierce to Spartanburgby car, plane, bus (Flixbus, Greyhound), shuttle, train, bus, or bus (Flixbus)

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There are 7 ways to get from Fort Pierce to Spartanburg by car, plane, bus (Flixbus, Greyhound), shuttle, train, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Asheville Regional Airport, drive

    best
    1. Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Spartanburgcar car
    5h 1m
    $86–395

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Atlanta Bus Station to Spartanburgbus bus Greyhound US0670
    17h 3m
    $130–209

  3. Drive  601.5 mi

    1. Drive from Fort Pierce to Spartanburgcar car 601.5 mi
    9h 51m
    $107–154

  4. Shuttle to Orlando, fly to Greenville–Spartanburg International Airport

    1. Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane plane MCO - GSP
    6h 27m
    $223–703

  5. Fly Vero Beach Municipal Airport to Charlotte Douglas International Airport, train

    1. Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane plane VRB - CLT
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    6h 1m
    $203–741

  6. Bus to Miami International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Greenville–Spartanburg International Airport (GSP)plane plane MIA - GSP
    7h 7m
    $177–664

  7. Bus via Sandy Springs

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Atlanta to Servicios Zapata - Spartanburgbus bus Charlotte
    18h 57m
    $136–220

Orlando Sanford (SFB) to Asheville Regional Airport (AVL) flights

Calendar13Weekly Planes
Duration1h 40mAverage Duration
Ticket$59Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Pierce to Spartanburg.ExpandLaunch map view
  • Distance: 643 mi
  • Duration: 5h 1m

What companies run services between Fort Pierce, FL, USA and Spartanburg, SC, USA?

You can take a bus from Orange Ave & N 9th St to Spartanburg via Wheeler Ter & Okeechobee Rd, Fort Pierce, Port St Lucie, Atlanta Bus Station, and Spartanburg in around 17h 3m.

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