There are 7 ways to get from Fort Pierce to Spartanburg by car, plane, bus (Flixbus, Greyhound), shuttle, train, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly to Asheville Regional Airport, drive
best- Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
4h 52m$86–397Bus
- Take the bus from Port St Lucie to Atlanta Bus Stationbus FlixBus N2401
- Take the bus from Atlanta Bus Station to Spartanburgbus Greyhound US0670
17h 3m$123–194Drive 601.5 mi
- Drive from Fort Pierce to Spartanburgcar 601.5 mi
9h 51m$110–159Shuttle to Orlando, fly to Greenville–Spartanburg International Airport
- Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airport
- Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane MCO - GSP
6h 27m$218–703Fly Vero Beach Municipal Airport to Charlotte Douglas International Airport, train
- Fly from Vero Beach Municipal Airport (VRB) to Charlotte Douglas International Airport (CLT)plane VRB - CLT
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
5h 52m$174–681Bus to Fort Lauderdale–Hollywood International Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Fort Pierce to Fort Lauderdale Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Greenville–Spartanburg International Airport (GSP)plane FLL - GSP
6h 21m$211–545Bus via Sandy Springs
- Take the bus from Port St Lucie to Atlanta Bus Stationbus FlixBus N2401
- Take the bus from Atlanta to Servicios Zapata - Spartanburgbus Charlotte
18h 57m$131–210
Orlando Sanford (SFB) to Asheville Regional Airport (AVL) flights
Comparing Your Travel Options
The cheapest way to get from Fort Pierce to Spartanburg is to drive which costs $110 - $160 and takes 9h 51m.
The fastest way to get from Fort Pierce to Spartanburg is to drive and fly which takes 4h 52m and costs $85 - $400.
No, there is no direct bus from Fort Pierce to Spartanburg. However, there are services departing from Orange Ave & N 9th St and arriving at Spartanburg via Fort Pierce, Port St Lucie and Atlanta Bus Station. The journey, including transfers, takes approximately 17h 3m.
The distance between Fort Pierce and Spartanburg is 647 miles. The road distance is 605 miles.
The best way to get from Fort Pierce to Spartanburg without a car is to bus which takes 17h 3m and costs $120 - $200.
It takes approximately 4h 52m to get from Fort Pierce to Spartanburg, including transfers.
Fort Pierce to Spartanburg bus services, operated by Flixbus USA, depart from Port St Lucie station.
Fort Pierce to Spartanburg bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Fort Pierce to Spartanburg is 605 miles. It takes approximately 9h 51m to drive from Fort Pierce to Spartanburg.
There are 80+ hotels available in Spartanburg.
What companies run services between Fort Pierce, FL, USA and Spartanburg, SC, USA?
You can take a bus from Orange Ave & N 9th St to Spartanburg via Wheeler Ter & Okeechobee Rd, Fort Pierce, Port St Lucie, Atlanta Bus Station, and Spartanburg in around 17h 3m.
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $55–350
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 51m
- When
- Friday, Thursday, Sunday, and Monday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Orlando to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $90–550
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Orlando to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $90–550
Flights from Vero Beach Municipal Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–550
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $120–650
- Website
- flybreeze.com
Flights from Orlando to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, Thursday, and Sunday
- Estimated price
- $180–1,200
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 5m
- When
- Monday and Friday
- Estimated price
- $130–310
- Website
- southwest.com
Flights from Fort Lauderdale–Hollywood International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 22m
- When
- Sunday
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to Spartanburg Station
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $21–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Port St Lucie to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Port St Lucie to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Spartanburg
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $28–45
- Website
- Greyhound
- Phone
- +1 772-343-0217
- Website
- Smart Shuttle Line, Inc.
Shuttle from Fort Pierce, FL - Dunkin' Donuts to Orlando Airport
- Ave. Duration
- 1h 57m
- Frequency
- 4 times a day
- Estimated price
- $70–85
- Schedules at
- Smart Shuttle Line, Inc.
- one passenger
- $70–85
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Fort Pierce to Fort Lauderdale Airport
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $25–35
- Website
- RedCoach
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Servicios Zapata - Spartanburg
- Ave. Duration
- 4h 4m
- Frequency
- Once daily
- Estimated price
- $35–60
- Schedules at
- Tornado Bus Company
- Adult
- $35–60
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide














