Rome2Rio

How to get fromFort Smith to Mayo Clinicby car, plane, or bus

Find Transport to Mayo Clinic

See all options

There are 6 ways to get from Fort Smith to Mayo Clinic by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Northwest Arkansas Regional Airport, fly to Rochester

    best
    1. Drive from Fort Smith to Northwest Arkansas Regional Airport (XNA)car car
    2. Fly from Northwest Arkansas Regional Airport (XNA) to Rochester (RST)plane plane XNA - RST
    6h 37m
    $85–470

  2. Bus via Kansas City

    1. Take the bus from Fort Smith Van Buren to Kansas Citybus bus
    2. Take the bus from Kansas City to St. Paulbus bus
    3. Take the bus from St. Paul to Rochesterbus bus
    17h 11m
    $207–300

  3. Drive  681.7 mi

    1. Drive from Fort Smith to Mayo Cliniccar car 681.7 mi
    11h 27m
    $125–180

  4. Drive to Northwest Arkansas Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Fort Smith to Northwest Arkansas Regional Airport (XNA)car car
    2. Fly from Northwest Arkansas Regional Airport (XNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane XNA - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 27m
    $149–550

  5. Fly Fort Smith Municipal Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Fort Smith Municipal Airport (FSM) to Minneapolis–Saint Paul International Airport (MSP)plane plane FSM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h
    $167–659

  6. Bus

    1. Take the bus from Fort Smith Van Buren to Tulsabus bus
    2. Take the bus from Tulsa to St. Paulbus bus
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    22h 23m
    $256–348

Northwest Arkansas Regional Airport (XNA) to Rochester (RST) flights

Calendar48Weekly Planes
Duration5h 5mAverage Duration
Ticket$74Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Fort Smith to Mayo Clinic.ExpandLaunch map view
  • Distance: 620.3 mi
  • Duration: 6h 37m

What companies run services between Fort Smith, AR, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Fort Smith to Mayo Clinic via Fort Smith Van Buren, Kansas City, St. Paul, and Rochester in around 17h 11m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides