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How to get fromFort Wayne to Knoxvilleby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 6 ways to get from Fort Wayne to Knoxville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Fort Wayne International Airport (FWA) to Mcghee Tyson Airport (TYS)plane plane FWA - TYS
    4h 26m
    $212–764

  2. Drive 404.2 mi

    cheapest
    1. Drive from Fort Wayne to Knoxvillecar car 404.2 mi
    7h 57m
    $74–107

  3. Bus

    1. Take the bus from Fort Wayne, IN to Toledobus bus
    2. Take the bus from Toledo Bus Stop to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    29h 38m
    $300–454

  4. Bus, train

    1. Take the bus from Fort Wayne, IN to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    32h 37m
    $385–674

  5. Bus via Columbus

    1. Take the bus from Fort Wayne, IN to Columbus - Mound Stbus bus
    2. Take the bus from Columbus, OH to New York, NYbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    32h 33m
    $225–281

  6. Bus, train via Farragut

    1. Take the bus from Fort Wayne, IN to Toledobus bus
    2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    32h 41m
    $430–764

Fort Wayne International Airport (FWA) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration5h 2mAverage Duration
Ticket$122Cheapest Price
See schedules

Questions & Answers

Map of how to get from Fort Wayne to Knoxville.ExpandLaunch map view
  • Distance: 389.1 mi
  • Duration: 4h 26m

What companies run services between Fort Wayne, IN, USA and Knoxville, TN, USA?

Delta, American Airlines, and two other airlines fly from Fort Wayne International Airport (FWA) to Mcghee Tyson Airport (TYS) every 2 hours. Alternatively, you can take a bus from Wal-Mart to Knoxville via Fort Wayne, IN, Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 29h 38m.

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