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How to get fromFort Wayne to Mayo Clinicby plane, bus, train, car, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Fort Wayne to Mayo Clinic by plane, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Fort Wayne International Airport (FWA) to Rochester (RST)plane plane FWA - RST
    5h 47m
    $93–424

  2. Drive  502.3 mi

    cheapest
    1. Drive from Fort Wayne to Mayo Cliniccar car 502.3 mi
    8h 57m
    $92–133

  3. Bus via Chicago

    1. Take the bus from Fort Wayne, IN to Chicagobus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    15h 5m
    $93–186

  4. Bus, train

    1. Take the bus from Fort Wayne, IN to Goshen, INbus bus
    2. Take the train from Elkhart Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    18h 19m
    $161–382

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Fort Wayne International Airport (FWA) to Minneapolis–Saint Paul International Airport (MSP)plane plane FWA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 14m
    $164–536

  6. Bus

    1. Take the bus from Fort Wayne, IN to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    15h 25m
    $94–176

Fort Wayne to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration15h 5mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Fort Wayne to Mayo Clinic.ExpandLaunch map view
  • Distance: 445.3 mi
  • Duration: 5h 47m

What companies run services between Fort Wayne, IN, USA and Mayo Clinic, MN, USA?

United Airlines, American Airlines, and Delta fly from Fort Wayne International Airport (FWA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Wal-Mart to Mayo Clinic via Fort Wayne, IN, Chicago, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 15h 5m.

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