There are 6 ways to get from Fort Wayne to Sikeston by bus, taxi, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from Ft Wayne Citilink Central Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
12h 7m$173–261Drive 450.9 mi
cheapest- Drive from Fort Wayne to Sikestoncar 450.9 mi
7h 32m$78–112Bus, train, drive
- Take the bus from Fort Wayne to Garybus
- Take the train from Homewood to Fulton Amtrak Stationtrain
- Drive from Fulton Amtrak Station to Sikestoncar
16h 5m$247–412Fly to Barkley Regional Airport, drive
- Fly from Fort Wayne International Airport (FWA) to Barkley Regional Airport (PAH)plane FWA - PAH
- Drive from Barkley Regional Airport (PAH) to Sikestoncar
7h 18m$106–418Bus
- Take the bus from Fort Wayne to Chicagobus Bsb 21 / ...
- Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus Milwaukee
15h 13m$130–199Fly to Williamson County Regional Airport, bus
- Fly from Fort Wayne International Airport (FWA) to Williamson County Regional Airport (MWA)plane FWA - MWA
- Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus
8h 39m$147–475
Fort Wayne International Airport (FWA) to Barkley Regional Airport (PAH) flights
Comparing Your Travel Options
The cheapest way to get from Fort Wayne to Sikeston is to drive which costs $75 - $120 and takes 7h 32m.
The fastest way to get from Fort Wayne to Sikeston is to fly and drive which takes 7h 18m and costs $100 - $420.
No, there is no direct bus from Fort Wayne to Sikeston. However, there are services departing from Wal-Mart and arriving at Flying J - Matthews via Fort Wayne, Harrison & Jefferson, Cicero & 24th Place Terminal and Tornado Bus Co - Chicago. The journey, including transfers, takes approximately 15h 13m.
The distance between Fort Wayne and Sikeston is 519 miles. The road distance is 453.5 miles.
The best way to get from Fort Wayne to Sikeston without a car is to bus and taxi which takes 12h 7m and costs $170 - $270.
It takes approximately 12h 7m to get from Fort Wayne to Sikeston, including transfers.
Fort Wayne to Sikeston bus services, operated by Barons Bus, depart from Fort Wayne station.
Fort Wayne to Sikeston bus services, operated by Barons Bus, arrive at Chicago station.
Sikeston is 1h behind Fort Wayne. It is currently 9:37 AM in Fort Wayne and 8:37 AM in Sikeston.
Yes, the driving distance between Fort Wayne to Sikeston is 453 miles. It takes approximately 7h 32m to drive from Fort Wayne to Sikeston.
What companies run services between Fort Wayne, IN, USA and Sikeston, MO, USA?
You can take a bus from Wal-Mart to Sikeston via Fort Wayne, Chicago, Harrison & Jefferson, Cicero & 24th Place Terminal, Tornado Bus Co - Chicago, and Flying J - Matthews in around 15h 13m.
- Website
- aa.com
Flights from Fort Wayne International Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $55–340
Flights from Fort Wayne International Airport to Williamson County Regional Airport via Charlotte, Chicago O'Hare
- Ave. Duration
- 11h 42m
- When
- Every day
- Estimated price
- $100–490
- Website
- united.com
Flights from Fort Wayne International Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $60–360
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Homewood to Fulton Amtrak Station
- Ave. Duration
- 6h 59m
- Frequency
- Once daily
- Estimated price
- $210–330
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ft Wayne Citilink Central Station to Indianapolis Union Station
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Every 4 hours
- Estimated price
- $40–70
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Fort Wayne to Gary
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $14–50
- Website
- Barons Bus
Bus from Fort Wayne to Chicago
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $17–55
- Website
- Barons Bus
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Tornado Bus Co - Chicago to Flying J - Matthews
- Ave. Duration
- 7h 24m
- Frequency
- Once daily
- Estimated price
- $80–100
- Schedules at
- Tornado Bus Company
- Adult
- $80–100
Bus from Marathon Gas Station - Marion to Flying J - Matthews
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
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Booking & Getting There
There are 13+ hotels available in Sikeston.











