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How to get fromFort Wayne to St. Louisby bus (Greyhound), bus, train, car, plane, or bus (Flixbus)

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There are 5 ways to get from Fort Wayne to St. Louis by bus (Greyhound), bus, train, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Ft Wayne Citilink Central Station to Indianapolis Union Stationbus bus Greyhound US0112
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    8h 27m
    $54–106

  2. Bus, train

    1. Take the bus from Fort Wayne, IN to Chicagobus bus Columbus / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    11h 7m
    $103–236

  3. Drive 366.1 mi

    1. Drive from Fort Wayne to St. Louiscar car 366.1 mi
    6h 9m
    $67–97

  4. Fly

    1. Fly from Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL)plane plane FWA - STL
    5h 9m
    $115–517

  5. Bus via Chicago

    1. Take the bus from Fort Wayne, IN to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    12h 7m
    $63–136

Fort Wayne to St. Louis by bus (Greyhound)

Calendar7Weekly Buses
Duration8h 27mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

Map of how to get from Fort Wayne to St. Louis.ExpandLaunch map view
  • Distance: 369.2 mi
  • Duration: 8h 27m

What companies run services between Fort Wayne, IN, USA and St. Louis, MO, USA?

You can take a bus from Wal-Mart to St Louis Bus Station via Ft Wayne Citilink Central Station and Indianapolis Union Station in around 8h 27m. Alternatively, American Airlines, United Airlines, and Delta fly from Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL) hourly.

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