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How to get fromFour Seasons Hotel St. Louis to Hyatt Regency Chicagoby train (Amtrak), bus (Flixbus), car, train, plane, or bus

Find Transport to Hyatt Regency Chicago

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There are 6 ways to get from Four Seasons Hotel St. Louis to Hyatt Regency Chicago by train (Amtrak), bus (Flixbus), car, train, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    6h 37m
    $90–196

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    7h 56m
    $54–89

  3. Drive 292.9 mi

    1. Drive from Four Seasons Hotel St. Louis to Hyatt Regency Chicagocar car 292.9 mi
    5h 6m
    $54–78

  4. Train, fly to Chicago Midway International Airport

    1. Take the train from CONVENTION CENTER station to FOREST PARK DEBALIVIERE stationtrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    4h 2m
    $62–380

  5. Train, fly to Chicago O'Hare International Airport

    1. Take the train from CONVENTION CENTER station to FOREST PARK DEBALIVIERE stationtrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    4h 15m
    $278–710

  6. Fly to General Mitchell International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    6h 16m
    $522–900

Four Seasons Hotel St. Louis to Hyatt Regency Chicago by foot, train, and bus (Amtrak)

Calendar38Weekly Services
Duration6h 37mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Four Seasons Hotel St. Louis to Hyatt Regency Chicago.ExpandLaunch map view
  • Distance: 285 mi
  • Duration: 6h 37m

What companies run services between Four Seasons Hotel St. Louis, MO, USA and Hyatt Regency Chicago, IL, USA?

Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $85–190 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station 4 times a day. Tickets cost $50–85 and the journey takes 6h 5m.

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