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How to get fromFramingham to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

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There are 9 ways to get from Framingham to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Chicago Midway International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane plane BOS - MDW
    4h 56m
    $96–464

  2. Train to Theodore Francis Green State Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the train from Back Bay to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Chicago O'Hare International Airport (ORD)plane plane PVD - ORD
    7h 36m
    $75–370

  3. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Chicago Union Stationtrain train Lake Shore Limited
    21h 47m
    $240–600

  4. Bus

    1. Take the bus from Framingham to Springfield Union Stationbus bus
    2. Take the bus from Springfield Union Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    26h 45m
    $172–273

  5. Drive  961.8 mi

    1. Drive from Framingham to Chicagocar car 961.8 mi
    16h 28m
    $176–254

  6. Fly Boston Logan Airport to Chicago O'Hare International Airport

    1. Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane plane BOS - ORD
    5h 13m
    $611–914

  7. Bus to Manchester Airport, fly to Chicago Midway International Airport

    1. Take the bus from Boston to Boston Manchester Airportbus bus
    2. Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane plane MHT - MDW
    7h 7m
    $134–678

  8. Train to Theodore Francis Green State Airport, fly to Chicago Midway International Airport

    1. Take the train from Back Bay to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Chicago Midway International Airport (MDW)plane plane PVD - MDW
    7h 29m
    $95–450

  9. Train to Bradley International Airport, fly to Chicago Midway International Airport

    1. Take the train from Framingham Amtrak to Springfieldtrain train
    2. Fly from Bradley International Airport (BDL) to Chicago Midway International Airport (MDW)plane plane BDL - MDW
    7h 46m
    $105–492

Framingham to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration21h 47mAverage Duration
Ticket$240Cheapest Price
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Comparing Your Travel Options

Map of how to get from Framingham to Chicago.ExpandLaunch map view
  • Distance: 892.4 mi
  • Duration: 4h 56m

What companies run services between Framingham, MA, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, Amtrak operates a train from Framingham Amtrak to Chicago Union Station once daily. Tickets cost $240–600 and the journey takes 21h 47m.

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